| Disease ID | Disease name | Source of annotation with ACAT1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 203750 | ALPHA-METHYLACETOACETIC ACIDURIA | OMIM, HUMSAVAR | link to OMIM | 1 | ACAT1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Lysine degradation | hsa00310 | 7.01 |
| Pyruvate metabolism | hsa00620 | 7.45 |
| Terpenoid backbone biosynthesis | hsa00900 | 8.31 |
| Metabolic pathways | hsa01100 | 2.49 |
| Glyoxylate and dicarboxylate metabolism | hsa00630 | 8.07 |
| Fatty acid degradation | hsa00071 | 7.15 |
| Synthesis and degradation of ketone bodies | hsa00072 | 9.6 |
| Carbon metabolism | hsa01200 | 6.03 |
| Valine, leucine and isoleucine degradation | hsa00280 | 7.09 |
| Propanoate metabolism | hsa00640 | 7.81 |
| Tryptophan metabolism | hsa00380 | 7.34 |
| Fatty acid metabolism | hsa01212 | 7.07 |
| Butanoate metabolism | hsa00650 | 7.96 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Ketone body metabolism | R-HSA-74182 | 10.66 |
| Synthesis of Ketone Bodies | R-HSA-77111 | 10.98 |
| Metabolism of amino acids and derivatives | R-HSA-71291 | 5.4 |
| Branched-chain amino acid catabolism | R-HSA-70895 | 8.89 |
| Utilization of Ketone Bodies | R-HSA-77108 | 11.4 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Fatty acid, triacylglycerol, and ketone body metabolism | R-HSA-535734 | 5.44 |
| Metabolism of lipids and lipoproteins | R-HSA-556833 | 3.79 |
| GO term | GO ID | GO IC |
|---|---|---|
| transferase activity, transferring acyl groups other than amino-acyl groups | GO:0016747 | 4.37 |
| coenzyme binding | GO:0050662 | 4.53 |
| metal ion binding | GO:0046872 | 1.41 |
| transferase activity, transferring acyl groups | GO:0016746 | 4.2 |
| acetyl-CoA C-acyltransferase activity | GO:0003988 | 7.95 |
| cation binding | GO:0043169 | 1.4 |
| acetyltransferase activity | GO:0016407 | 5.1 |
| enzyme binding | GO:0019899 | 2.27 |
| ion binding | GO:0043167 | 1.36 |
| catalytic activity | GO:0003824 | 1.05 |
| transferase activity | GO:0016740 | 1.95 |
| cofactor binding | GO:0048037 | 4.16 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| C-acetyltransferase activity | GO:0016453 | 8.35 |
| protein dimerization activity | GO:0046983 | 2.72 |
| acetyl-CoA C-acetyltransferase activity | GO:0003985 | 8.64 |
| C-acyltransferase activity | GO:0016408 | 7.1 |
| identical protein binding | GO:0042802 | 2.63 |
| protein homodimerization activity | GO:0042803 | 3.16 |