Gene table of ADA : adenosine deaminase

Gene-disease associations table

Disease IDDisease nameSource of annotation with ADAOMIM linkNumber of associated genesgenes
102700SEVERE COMBINED IMMUNODEFICIENCY, AUTOSOMAL RECESSIVE, T CELL-NEGATIVE, B CELL-NEGATIVE, NK CELL-NEGATIVE, DUE TO ADENOSINE DEAMINASE DEFICIENCYClinVar, OMIM, HUMSAVAR link to OMIM 1ADA

Download the gene annotation in CSV format

Annotation of the gene ADA

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Primary immunodeficiencyhsa053407.52
Metabolic pathwayshsa011002.49
Purine metabolismhsa002305.28
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Purine salvageR-HSA-742179.28
Metabolism of nucleotidesR-HSA-158696.7
MetabolismR-HSA-14307282.34
Purine metabolismR-HSA-738477.94
Associated GO terms for Molecular function
GO termGO IDGO IC
hydrolase activityGO:00167871.9
transition metal ion bindingGO:00469142.48
cation bindingGO:00431691.4
carbohydrate derivative bindingGO:00973672.03
organic cyclic compound bindingGO:00971591.05
hydrolase activity, acting on carbon-nitrogen (but not peptide) bondsGO:00168104.76
heterocyclic compound bindingGO:19013631.06
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidinesGO:00168146.21
ion bindingGO:00431671.36
small molecule bindingGO:00360941.89
catalytic activityGO:00038241.05
deaminase activityGO:00192396.24
nucleoside bindingGO:00018822.21
bindingGO:00054880.18
protein bindingGO:00055150.46
metal ion bindingGO:00468721.41
adenosine deaminase activityGO:00040007.34
purine nucleoside bindingGO:00018832.22
zinc ion bindingGO:00082702.66