Gene table of ADCY5 : adenylate cyclase 5

Gene-disease associations table

Disease IDDisease nameSource of annotation with ADCY5OMIM linkNumber of associated genesgenes
606703DYSKINESIA, FAMILIAL, WITH FACIAL MYOKYMIAClinVar, OMIM, HUMSAVAR link to OMIM 1ADCY5

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Annotation of the gene ADCY5

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Platelet activationhsa046115.66
cGMP-PKG signaling pathwayhsa040225.32
cAMP signaling pathwayhsa040245.05
Retrograde endocannabinoid signalinghsa047236.03
Cholinergic synapsehsa047255.88
Glutamatergic synapsehsa047245.84
GABAergic synapsehsa047276.24
Serotonergic synapsehsa047265.84
Dopaminergic synapsehsa047285.69
Dilated cardiomyopathyhsa054146.08
Oxytocin signaling pathwayhsa049215.4
Chemokine signaling pathwayhsa040625.19
HTLV-I infectionhsa051664.59
Vascular smooth muscle contractionhsa042705.74
Gap junctionhsa045406.24
Pathways in cancerhsa052003.98
Oocyte meiosishsa041145.91
GnRH signaling pathwayhsa049126.18
Ovarian steroidogenesishsa049137.07
Rap1 signaling pathwayhsa040154.97
Insulin secretionhsa049116.18
Melanogenesishsa049165.97
Progesterone-mediated oocyte maturationhsa049146.18
Estrogen signaling pathwayhsa049156.11
Thyroid hormone synthesishsa049186.56
Circadian entrainmenthsa047136.11
Salivary secretionhsa049706.23
Gastric acid secretionhsa049716.48
Pancreatic secretionhsa049726.07
Bile secretionhsa049766.56
Morphine addictionhsa050326.15
Cocaine addictionhsa050307.07
Amphetamine addictionhsa050316.62
Alcoholismhsa050345.59
Purine metabolismhsa002305.28
Inflammatory mediator regulation of TRP channelshsa047506.07
Adrenergic signaling in cardiomyocyteshsa042615.44
Parkinson's diseasehsa050125.59
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Phospholipase C-mediated cascade; FGFR2R-HSA-56542217.37
PLCG1 events in ERBB2 signalingR-HSA-12519327.85
DAG and IP3 signalingR-HSA-14895097.98
Phospholipase C-mediated cascade; FGFR3R-HSA-56542277.52
Ca-dependent eventsR-HSA-1119968.18
Phospholipase C-mediated cascade; FGFR4R-HSA-56542287.46
G alpha (z) signalling eventsR-HSA-4185977.46
Immune SystemR-HSA-1682562.37
Transmembrane transport of small moleculesR-HSA-3825513.79
MetabolismR-HSA-14307282.34
Downstream signal transductionR-HSA-1867634.65
Signaling by HedgehogR-HSA-53583515.79
Adenylate cyclase activating pathwayR-HSA-1706609.66
Vasopressin regulates renal water homeostasis via AquaporinsR-HSA-4320407.56
G alpha (s) signalling eventsR-HSA-4185555.99
Calmodulin induced eventsR-HSA-1119338.28
Adenylate cyclase inhibitory pathwayR-HSA-1706709.18
PKA-mediated phosphorylation of CREBR-HSA-1119318.89
Downstream signaling of activated FGFR1R-HSA-56546874.71
CaM pathwayR-HSA-1119978.28
PKA activationR-HSA-1636158.98
Signalling by NGFR-HSA-1665204.23
Adrenaline,noradrenaline inhibits insulin secretionR-HSA-4000428.18
PKA activation in glucagon signallingR-HSA-1643788.89
GABA receptor activationR-HSA-9774437.2
Phospholipase C-mediated cascade: FGFR1R-HSA-56542197.43
G alpha (i) signalling eventsR-HSA-4185945.1
Neuronal SystemR-HSA-1123164.82
Signaling by GPCRR-HSA-3727902.68
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic CellR-HSA-1123145.85
Transmission across Chemical SynapsesR-HSA-1123155.28
Signaling by FGFR4R-HSA-56547434.69
Signaling by FGFR3R-HSA-56547414.69
Signaling by FGFRR-HSA-1902364.67
Downstream signaling of activated FGFR3R-HSA-56547084.71
GPCR downstream signalingR-HSA-3883963.07
GABA B receptor activationR-HSA-9774447.7
Innate Immune SystemR-HSA-1682493.17
Integration of energy metabolismR-HSA-1636856.24
Aquaporin-mediated transportR-HSA-4457177.31
Signaling by ERBB2R-HSA-12279864.66
Activation of GABAB receptorsR-HSA-9913657.7
DAP12 signalingR-HSA-24244914.64
Hedgehog 'off' stateR-HSA-56107876.19
Downstream signaling of activated FGFR2R-HSA-56546964.71
PLC-gamma1 signallingR-HSA-1670217.89
Signaling by EGFRR-HSA-1779294.59
NGF signalling via TRKA from the plasma membraneR-HSA-1870374.51
Glucagon signaling in metabolic regulationR-HSA-1633597.94
EGFR interacts with phospholipase C-gammaR-HSA-2127187.89
Regulation of insulin secretionR-HSA-4223566.66
PLC beta mediated eventsR-HSA-1120437.52
G-protein mediated eventsR-HSA-1120407.49
Signaling by FGFR2R-HSA-56547384.68
Signaling by FGFR1R-HSA-56547364.69
Opioid SignallingR-HSA-1118856.64
DAP12 interactionsR-HSA-21721274.56
Inhibition of adenylate cyclase pathwayR-HSA-9972699.18
Downstream signaling of activated FGFR4R-HSA-56547164.71
Signaling by PDGFR-HSA-1867974.53
Signal TransductionR-HSA-1625821.78
Glucagon-like Peptide-1 (GLP1) regulates insulin secretionR-HSA-3816767.59
Associated GO terms for Molecular function
GO termGO IDGO IC
purine ribonucleoside triphosphate bindingGO:00356392.22
enzyme bindingGO:00198992.27
adenylate cyclase activityGO:00040166.74
bindingGO:00054880.18
ion bindingGO:00431671.36
heterocyclic compound bindingGO:19013631.06
purine nucleoside bindingGO:00018832.22
nucleoside bindingGO:00018822.21
cation bindingGO:00431691.4
lyase activityGO:00168294.53
phosphorus-oxygen lyase activityGO:00168496.6
nucleotide bindingGO:00001661.96
nucleoside phosphate bindingGO:19012651.96
ribonucleoside bindingGO:00325492.22
purine nucleotide bindingGO:00170762.19
metal ion bindingGO:00468721.41
ATP bindingGO:00055242.43
small molecule bindingGO:00360941.89
catalytic activityGO:00038241.05
adenylate cyclase bindingGO:00081797.66
adenyl nucleotide bindingGO:00305542.4
carbohydrate derivative bindingGO:00973672.03
organic cyclic compound bindingGO:00971591.05
cyclase activityGO:00099756.6
adenyl ribonucleotide bindingGO:00325592.41
protein bindingGO:00055150.46
purine ribonucleotide bindingGO:00325552.2
protein dimerization activityGO:00469832.72
protein heterodimerization activityGO:00469823.64
purine ribonucleoside bindingGO:00325502.22
ribonucleotide bindingGO:00325532.19