Gene table of ADRA2B : adrenoceptor alpha 2B

Gene-disease associations table

Disease IDDisease nameSource of annotation with ADRA2BOMIM linkNumber of associated genesgenes
PS601068EPILEPSY, FAMILIAL ADULT MYOCLONICOMIM link to OMIM 2CNTN2, ADRA2B

Download the gene annotation in CSV format

Annotation of the gene ADRA2B

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
cGMP-PKG signaling pathwayhsa040225.32
Neuroactive ligand-receptor interactionhsa040804.58
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Platelet Aggregation (Plug Formation)R-HSA-760097.77
Amine ligand-binding receptorsR-HSA-3752807.59
Signaling by GPCRR-HSA-3727902.68
G alpha (i) signalling eventsR-HSA-4185945.1
G alpha (z) signalling eventsR-HSA-4185977.46
AdrenoceptorsR-HSA-3906969.81
Class A/1 (Rhodopsin-like receptors)R-HSA-3730764.69
Adrenaline signalling through Alpha-2 adrenergic receptorR-HSA-39202311.4
GPCR downstream signalingR-HSA-3883963.07
GPCR ligand bindingR-HSA-5007924.19
HemostasisR-HSA-1095823.98
Signal TransductionR-HSA-1625821.78
Platelet activation, signaling and aggregationR-HSA-760025.15
Associated GO terms for Molecular function
GO termGO IDGO IC
G-protein coupled receptor activityGO:00049302.95
GO:00513797.95
GO:00049367.95
protein bindingGO:00055150.46
adrenergic receptor activityGO:00049356.97
catecholamine bindingGO:19013386.97
GO:00049388.64
molecular transducer activityGO:00600892.32
transmembrane signaling receptor activityGO:00048882.57
bindingGO:00054880.18
signal transducer activityGO:00048712.28
organic cyclic compound bindingGO:00971591.05
signaling receptor activityGO:00380232.49
G-protein coupled amine receptor activityGO:00082275.83
transmembrane receptor activityGO:00996002.53
receptor activityGO:00048722.32