Gene table of ADRB1 : adrenoceptor beta 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with ADRB1	OMIM link	Number of associated genes	genes
607276	RESTING HEART RATE, VARIATION IN	ClinVar, OMIM	link to OMIM	1	ADRB1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Salivary secretion	hsa04970	6.23
Gap junction	hsa04540	6.24
cGMP-PKG signaling pathway	hsa04022	5.32
Dilated cardiomyopathy	hsa05414	6.08
Calcium signaling pathway	hsa04020	5.22
cAMP signaling pathway	hsa04024	5.05
Endocytosis	hsa04144	4.92
Neuroactive ligand-receptor interaction	hsa04080	4.58
Adrenergic signaling in cardiomyocytes	hsa04261	5.44

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Amine ligand-binding receptors	R-HSA-375280	7.59
Signaling by GPCR	R-HSA-372790	2.68
GPCR downstream signaling	R-HSA-388396	3.07
Class A/1 (Rhodopsin-like receptors)	R-HSA-373076	4.69
GPCR ligand binding	R-HSA-500792	4.19
G alpha (s) signalling events	R-HSA-418555	5.99
Adrenoceptors	R-HSA-390696	9.81
Signal Transduction	R-HSA-162582	1.78

Associated GO terms for Molecular function

GO term	GO ID	GO IC
Ras guanyl-nucleotide exchange factor activity	GO:0005088	4.31
alpha-2A adrenergic receptor binding	GO:0031694	8.35
signaling receptor activity	GO:0038023	2.49
	GO:0051380	8.35
guanyl-nucleotide exchange factor activity	GO:0005085	4.02
molecular transducer activity	GO:0060089	2.32
protein dimerization activity	GO:0046983	2.72
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
G-protein coupled receptor binding	GO:0001664	4.18
molecular function regulator	GO:0098772	2.51
G-protein coupled receptor activity	GO:0004930	2.95
adrenergic receptor activity	GO:0004935	6.97
receptor signaling protein activity	GO:0005057	4.76
	GO:0004939	8.64
adrenergic receptor binding	GO:0031690	6.85
PDZ domain binding	GO:0030165	5.22
protein domain specific binding	GO:0019904	3.32
	GO:0004940	9.74
G-protein coupled amine receptor activity	GO:0008227	5.83
	GO:0051379	7.95
catecholamine binding	GO:1901338	6.97
transmembrane signaling receptor activity	GO:0004888	2.57
protein binding	GO:0005515	0.46
organic cyclic compound binding	GO:0097159	1.05
receptor binding	GO:0005102	2.43
protein heterodimerization activity	GO:0046982	3.64
transmembrane receptor activity	GO:0099600	2.53
receptor activity	GO:0004872	2.32