Gene table of ADRB2 : adrenoceptor beta 2

Gene-disease associations table

Disease ID	Disease name	Source of annotation with ADRB2	OMIM link	Number of associated genes	genes
600807	ASTHMA, SUSCEPTIBILITY TO	OMIM	link to OMIM	13	HLA-G, SCGB1A1, PLA2G7, PHF11, MUC7, TNF, HNMT, IL13, SPINK5, SCGB3A2, CCL11, ALOX5, ADRB2
601665	OBESITY	OMIM	link to OMIM	15	PPARGC1B, AGRP, PPARG, MC4R, ADRB3, CARTPT, UCP3, SIM1, POMC, ENPP1, ADRB2, SDC3, NR0B2, UCP1, GHRL

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Salivary secretion	hsa04970	6.23
cGMP-PKG signaling pathway	hsa04022	5.32
Calcium signaling pathway	hsa04020	5.22
cAMP signaling pathway	hsa04024	5.05
Endocytosis	hsa04144	4.92
Neuroactive ligand-receptor interaction	hsa04080	4.58
Adrenergic signaling in cardiomyocytes	hsa04261	5.44

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Amine ligand-binding receptors	R-HSA-375280	7.59
Signaling by GPCR	R-HSA-372790	2.68
GPCR downstream signaling	R-HSA-388396	3.07
Class A/1 (Rhodopsin-like receptors)	R-HSA-373076	4.69
GPCR ligand binding	R-HSA-500792	4.19
G alpha (s) signalling events	R-HSA-418555	5.99
Adrenoceptors	R-HSA-390696	9.81
Signal Transduction	R-HSA-162582	1.78

Associated GO terms for Molecular function

GO term	GO ID	GO IC
signaling receptor activity	GO:0038023	2.49
	GO:0051380	8.35
enzyme binding	GO:0019899	2.27
drug binding	GO:0008144	5.03
molecular transducer activity	GO:0060089	2.32
	GO:0031711	8.64
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
G-protein coupled receptor binding	GO:0001664	4.18
molecular function regulator	GO:0098772	2.51
G-protein coupled receptor activity	GO:0004930	2.95
adrenergic receptor activity	GO:0004935	6.97
protein dimerization activity	GO:0046983	2.72
	GO:0004939	8.64
G-protein alpha-subunit binding	GO:0001965	6.6
protein complex binding	GO:0032403	3.09
identical protein binding	GO:0042802	2.63
protein homodimerization activity	GO:0042803	3.16
potassium channel regulator activity	GO:0015459	5.93
ionotropic glutamate receptor binding	GO:0035255	6.56
glutamate receptor binding	GO:0035254	6.13
channel regulator activity	GO:0016247	4.88
	GO:0004941	9.74
adenylate cyclase binding	GO:0008179	7.66
G-protein coupled amine receptor activity	GO:0008227	5.83
	GO:0051379	7.95
	GO:0031713	9.74
organic cyclic compound binding	GO:0097159	1.05
transmembrane signaling receptor activity	GO:0004888	2.57
protein binding	GO:0005515	0.46
catecholamine binding	GO:1901338	6.97
dopamine binding	GO:0035240	7.34
receptor binding	GO:0005102	2.43
transmembrane receptor activity	GO:0099600	2.53
receptor activity	GO:0004872	2.32