Gene table of AKAP9 : A-kinase anchoring protein 9

Gene-disease associations table

Disease IDDisease nameSource of annotation with AKAP9OMIM linkNumber of associated genesgenes
PS192500LONG QT SYNDROMEClinVar, OMIM, HUMSAVAR link to OMIM 16ALG10, KCNJ5, KCNH2, CALM1, CALM2, KCNE1, ANK2, AKAP9, SCN5A, SCN4B, SNTA1, CACNA1C, KCNE2, KCNJ2, KCNQ1, CAV3
115000CARDIAC ARRHYTHMIAClinVar link to OMIM 25KCNE3, CACNB2, AKAP9, NPPA, KCNE1, SCN4B, CASQ2, KCNJ5, TANGO2, JUP, ANK2, KCNJ2, DSG2, NOS1AP, KCNJ8, LIG3, RYR2, CACNA1C, KCNE2, KCNH2, SCN5A, HCN4, SNTA1, SCN1B, KCNQ1

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Annotation of the gene AKAP9

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
CREB phosphorylation through the activation of CaMKIIR-HSA-4427299.08
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)R-HSA-24041924.85
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-8819074.26
NCAM signaling for neurite out-growthR-HSA-3751654.9
Signaling by InterleukinsR-HSA-4491474.71
Post NMDA receptor activation eventsR-HSA-4380647.85
Loss of Nlp from mitotic centrosomesR-HSA-3802597.03
Signaling by LeptinR-HSA-25865525.1
Frs2-mediated activationR-HSA-1709685.12
Cytokine Signaling in Immune systemR-HSA-12802153.74
Cell CycleR-HSA-16401703.89
IGF1R signaling cascadeR-HSA-24289244.85
Unblocking of NMDA receptor, glutamate binding and activationR-HSA-4380668.89
Ras activation uopn Ca2+ infux through NMDA receptorR-HSA-4429828.89
IRS-related events triggered by IGF1RR-HSA-24289284.85
Signaling by ERBB4R-HSA-12363944.7
Assembly of the primary ciliumR-HSA-56178335.44
IRS-mediated signallingR-HSA-1123994.87
MAPK1/MAPK3 signalingR-HSA-56849965.11
Downstream signaling of activated FGFR2R-HSA-56546964.71
Developmental BiologyR-HSA-12667383.48
RAF/MAP kinase cascadeR-HSA-56730015.15
Recruitment of mitotic centrosome proteins and complexesR-HSA-3802706.68
Downstream signaling of activated FGFR1R-HSA-56546874.71
MAPK family signaling cascadesR-HSA-56830574.89
Signalling by NGFR-HSA-1665204.23
Signaling by VEGFR-HSA-1941384.66
Signalling to p38 via RIT and RINR-HSA-1877065.12
Organelle biogenesis and maintenanceR-HSA-18522414.63
FCERI mediated MAPK activationR-HSA-28717964.32
Signaling by EGFRR-HSA-1779294.59
FRS-mediated FGFR2 signalingR-HSA-56547005.14
DAP12 interactionsR-HSA-21721274.56
FRS-mediated FGFR3 signalingR-HSA-56547065.14
Signaling by Insulin receptorR-HSA-747524.73
Loss of proteins required for interphase microtubule organization from the centrosomeR-HSA-3802847.03
Neuronal SystemR-HSA-1123164.82
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic CellR-HSA-1123145.85
Transmission across Chemical SynapsesR-HSA-1123155.28
Signaling by FGFR4R-HSA-56547434.69
G2/M TransitionR-HSA-692756.06
Signaling by FGFR3R-HSA-56547414.69
VEGFA-VEGFR2 PathwayR-HSA-44200974.7
GRB2 events in ERBB2 signalingR-HSA-19636405.15
Interleukin receptor SHC signalingR-HSA-9125265.09
Signaling by FGFRR-HSA-1902364.67
Downstream signaling of activated FGFR3R-HSA-56547084.71
Fc epsilon receptor (FCERI) signalingR-HSA-24542024.03
Immune SystemR-HSA-1682562.37
Centrosome maturationR-HSA-3802876.68
Downstream signaling of activated FGFR4R-HSA-56547164.71
Innate Immune SystemR-HSA-1682493.17
Mitotic G2-G2/M phasesR-HSA-4532746.04
Interleukin-2 signalingR-HSA-4519275.05
SHC1 events in ERBB2 signalingR-HSA-12501965.15
CREB phosphorylation through the activation of RasR-HSA-4427428.23
Signaling by ERBB2R-HSA-12279864.66
Anchoring of the basal body to the plasma membraneR-HSA-56209126.51
DAP12 signalingR-HSA-24244914.64
Interleukin-3, 5 and GM-CSF signalingR-HSA-5129884.99
Activation of NMDA receptor upon glutamate binding and postsynaptic eventsR-HSA-4427557.7
Cell Cycle, MitoticR-HSA-692784.16
Signaling by FGFR1R-HSA-56547364.69
SHC1 events in EGFR signalingR-HSA-1803365.15
NGF signalling via TRKA from the plasma membraneR-HSA-1870374.51
FRS-mediated FGFR1 signalingR-HSA-56546935.14
Prolonged ERK activation eventsR-HSA-1698935.11
FRS-mediated FGFR4 signalingR-HSA-56547125.14
Signaling by GPCRR-HSA-3727902.68
Signaling by FGFR2R-HSA-56547384.68
GRB2 events in EGFR signalingR-HSA-1798125.15
Signalling to ERKsR-HSA-1876875.04
Insulin receptor signalling cascadeR-HSA-747514.85
Signalling to RASR-HSA-1670445.08
ARMS-mediated activationR-HSA-1709845.12
Regulation of PLK1 Activity at G2/M TransitionR-HSA-25659426.66
Signaling by SCF-KITR-HSA-14335574.73
SOS-mediated signallingR-HSA-1124125.15
SHC1 events in ERBB4 signalingR-HSA-12503475.15
Signaling by PDGFR-HSA-1867974.53
Axon guidanceR-HSA-4224753.93
VEGFR2 mediated cell proliferationR-HSA-52189215.07
Signal TransductionR-HSA-1625821.78
Downstream signal transductionR-HSA-1867634.65
Associated GO terms for Molecular function
GO termGO IDGO IC
Ras guanyl-nucleotide exchange factor activityGO:00050884.31
protein kinase A bindingGO:00510186.02
protein bindingGO:00055150.46
organic cyclic compound bindingGO:00971591.05
potassium channel regulator activityGO:00154595.93
kinase activityGO:00163012.93
guanyl-nucleotide exchange factor activityGO:00050854.02
transferase activity, transferring phosphorus-containing groupsGO:00167722.77
structural molecule activityGO:00051983.1
protein complex scaffoldGO:00329475.5
catalytic activityGO:00038241.05
transferase activityGO:00167401.95
protein kinase A regulatory subunit bindingGO:00342376.97
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
channel regulator activityGO:00162474.88
ion channel bindingGO:00443255.02
molecular function regulatorGO:00987722.51
receptor bindingGO:00051022.43
heterocyclic compound bindingGO:19013631.06
bindingGO:00054880.18