| Disease ID | Disease name | Source of annotation with ALOX5 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 600807 | ASTHMA, SUSCEPTIBILITY TO | OMIM | link to OMIM | 13 | HLA-G, SCGB1A1, PLA2G7, PHF11, MUC7, TNF, HNMT, IL13, SPINK5, SCGB3A2, CCL11, ALOX5, ADRB2 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Ovarian steroidogenesis | hsa04913 | 7.07 |
| Arachidonic acid metabolism | hsa00590 | 6.79 |
| Toxoplasmosis | hsa05145 | 5.71 |
| Metabolic pathways | hsa01100 | 2.49 |
| Serotonergic synapse | hsa04726 | 5.84 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Synthesis of Lipoxins (LX) | R-HSA-2142700 | 10.4 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Synthesis of 5-eicosatetraenoic acids | R-HSA-2142688 | 10.4 |
| Arachidonic acid metabolism | R-HSA-2142753 | 7.34 |
| Metabolism of lipids and lipoproteins | R-HSA-556833 | 3.79 |
| Synthesis of Leukotrienes (LT) and Eoxins (EX) | R-HSA-2142691 | 8.59 |
| GO term | GO ID | GO IC |
|---|---|---|
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | GO:0016701 | 6.41 |
| GO:0004051 | 9.05 | |
| transition metal ion binding | GO:0046914 | 2.48 |
| dioxygenase activity | GO:0051213 | 5.25 |
| cation binding | GO:0043169 | 1.4 |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | GO:0016702 | 6.44 |
| ion binding | GO:0043167 | 1.36 |
| catalytic activity | GO:0003824 | 1.05 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| iron ion binding | GO:0005506 | 4.65 |
| metal ion binding | GO:0046872 | 1.41 |
| oxidoreductase activity | GO:0016491 | 3.12 |