| Disease ID | Disease name | Source of annotation with ANK2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS604772 | VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC | ClinVar | link to OMIM | 15 | TRDN, MYBPC3, TPM1, SCN5A, DMPK, LMNA, CALM1, DSP, RYR2, ANK2, TRPM4, KCNH2, LAMA4, CASQ2, DSG2 |
| PS192500 | LONG QT SYNDROME | ClinVar, OMIM, HUMSAVAR | link to OMIM | 16 | ALG10, KCNJ5, KCNH2, CALM1, CALM2, KCNE1, ANK2, AKAP9, SCN5A, SCN4B, SNTA1, CACNA1C, KCNE2, KCNJ2, KCNQ1, CAV3 |
| 115000 | CARDIAC ARRHYTHMIA | ClinVar | link to OMIM | 25 | KCNE3, CACNB2, AKAP9, NPPA, KCNE1, SCN4B, CASQ2, KCNJ5, TANGO2, JUP, ANK2, KCNJ2, DSG2, NOS1AP, KCNJ8, LIG3, RYR2, CACNA1C, KCNE2, KCNH2, SCN5A, HCN4, SNTA1, SCN1B, KCNQ1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Proteoglycans in cancer | hsa05205 | 5.02 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Axon guidance | R-HSA-422475 | 3.93 |
| Interaction between L1 and Ankyrins | R-HSA-445095 | 8.03 |
| L1CAM interactions | R-HSA-373760 | 6.19 |
| Developmental Biology | R-HSA-1266738 | 3.48 |
| GO term | GO ID | GO IC |
|---|---|---|
| protein binding, bridging | GO:0030674 | 4.68 |
| structural constituent of cytoskeleton | GO:0005200 | 5.12 |
| cytoskeletal adaptor activity | GO:0008093 | 6.97 |
| cytoskeletal protein binding | GO:0008092 | 3.02 |
| ATPase binding | GO:0051117 | 5.41 |
| enzyme binding | GO:0019899 | 2.27 |
| structural molecule activity | GO:0005198 | 3.1 |
| protein kinase binding | GO:0019901 | 3.44 |
| kinase binding | GO:0019900 | 3.32 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| ion channel binding | GO:0044325 | 5.02 |
| binding, bridging | GO:0060090 | 4.57 |
| spectrin binding | GO:0030507 | 6.48 |