Gene table of APOL1 : apolipoprotein L1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with APOL1	OMIM link	Number of associated genes	genes
PS603278	FOCAL SEGMENTAL GLOMERULOSCLEROSIS	ClinVar, OMIM, HUMSAVAR	link to OMIM	9	ACTN4, ANLN, INF2, TRPC6, PAX2, CD2AP, CRB2, MYO1E, APOL1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
African trypanosomiasis	hsa05143	7.68

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Scavenging of heme from plasma	R-HSA-2168880	5.61
Binding and Uptake of Ligands by Scavenger Receptors	R-HSA-2173782	5.38
Vesicle-mediated transport	R-HSA-5653656	4.33

Associated GO terms for Molecular function

GO term	GO ID	GO IC
substrate-specific transmembrane transporter activity	GO:0022891	2.9
anion transmembrane transporter activity	GO:0008509	4.43
substrate-specific transporter activity	GO:0022892	2.72
inorganic anion transmembrane transporter activity	GO:0015103	4.87
substrate-specific channel activity	GO:0022838	3.67
transporter activity	GO:0005215	2.57
ion channel activity	GO:0005216	3.71
lipid binding	GO:0008289	3.26
ion transmembrane transporter activity	GO:0015075	3.04
transmembrane transporter activity	GO:0022857	2.82
channel activity	GO:0015267	3.6
binding	GO:0005488	0.18
protein binding	GO:0005515	0.46
passive transmembrane transporter activity	GO:0022803	3.6
anion channel activity	GO:0005253	5.23
chloride channel activity	GO:0005254	5.36
chloride transmembrane transporter activity	GO:0015108	5.24