| Disease ID | Disease name | Source of annotation with ARHGDIA | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS256300 | NEPHROTIC SYNDROME | ClinVar, OMIM | link to OMIM | 14 | LAMB2, NUP93, NUP205, NPHS1, OPA1, NPHS2, ADCK4, NUP107, WT1, ARHGDIA, PTPRO, PLCE1, EMP2, DGKE |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Vasopressin-regulated water reabsorption | hsa04962 | 7.18 |
| Neurotrophin signaling pathway | hsa04722 | 5.78 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 9.81 |
| Signalling by NGF | R-HSA-166520 | 4.23 |
| p75NTR regulates axonogenesis | R-HSA-193697 | 9.66 |
| Signaling by Rho GTPases | R-HSA-194315 | 4.43 |
| Rho GTPase cycle | R-HSA-194840 | 6.04 |
| p75 NTR receptor-mediated signalling | R-HSA-193704 | 6.59 |
| Axonal growth stimulation | R-HSA-209563 | 10.98 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| heat shock protein binding | GO:0031072 | 5.24 |
| enzyme binding | GO:0019899 | 2.27 |
| small GTPase binding | GO:0031267 | 4.13 |
| GTPase binding | GO:0051020 | 4.05 |
| binding | GO:0005488 | 0.18 |
| molecular function regulator | GO:0098772 | 2.51 |
| anion binding | GO:0043168 | 4.17 |
| ion binding | GO:0043167 | 1.36 |
| fatty acid binding | GO:0005504 | 6.37 |
| Hsp90 protein binding | GO:0051879 | 6.37 |
| GDP-dissociation inhibitor activity | GO:0005092 | 7.17 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| GTPase activator activity | GO:0005096 | 4.11 |
| lipid binding | GO:0008289 | 3.26 |
| GO:0005094 | 8.64 | |
| Ras GTPase binding | GO:0017016 | 4.2 |
| protein kinase binding | GO:0019901 | 3.44 |
| GTPase regulator activity | GO:0030695 | 4.01 |
| Rho GTPase binding | GO:0017048 | 5.36 |
| monocarboxylic acid binding | GO:0033293 | 5.61 |
| nucleoside-triphosphatase regulator activity | GO:0060589 | 3.92 |
| kinase binding | GO:0019900 | 3.32 |
| carboxylic acid binding | GO:0031406 | 4.64 |
| protein binding | GO:0005515 | 0.46 |
| enzyme activator activity | GO:0008047 | 3.56 |