Disease ID | Disease name | Source of annotation with ARHGDIA | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS256300 | NEPHROTIC SYNDROME | ClinVar, OMIM | link to OMIM | 14 | LAMB2, NUP93, NUP205, NPHS1, OPA1, NPHS2, ADCK4, NUP107, WT1, ARHGDIA, PTPRO, PLCE1, EMP2, DGKE |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Vasopressin-regulated water reabsorption | hsa04962 | 7.18 |
Neurotrophin signaling pathway | hsa04722 | 5.78 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 9.81 |
Signalling by NGF | R-HSA-166520 | 4.23 |
p75NTR regulates axonogenesis | R-HSA-193697 | 9.66 |
Signaling by Rho GTPases | R-HSA-194315 | 4.43 |
Rho GTPase cycle | R-HSA-194840 | 6.04 |
p75 NTR receptor-mediated signalling | R-HSA-193704 | 6.59 |
Axonal growth stimulation | R-HSA-209563 | 10.98 |
Signal Transduction | R-HSA-162582 | 1.78 |
GO term | GO ID | GO IC |
---|---|---|
heat shock protein binding | GO:0031072 | 5.24 |
enzyme binding | GO:0019899 | 2.27 |
small GTPase binding | GO:0031267 | 4.13 |
GTPase binding | GO:0051020 | 4.05 |
binding | GO:0005488 | 0.18 |
molecular function regulator | GO:0098772 | 2.51 |
anion binding | GO:0043168 | 4.17 |
ion binding | GO:0043167 | 1.36 |
fatty acid binding | GO:0005504 | 6.37 |
Hsp90 protein binding | GO:0051879 | 6.37 |
GDP-dissociation inhibitor activity | GO:0005092 | 7.17 |
enzyme regulator activity | GO:0030234 | 2.85 |
GTPase activator activity | GO:0005096 | 4.11 |
lipid binding | GO:0008289 | 3.26 |
GO:0005094 | 8.64 | |
Ras GTPase binding | GO:0017016 | 4.2 |
protein kinase binding | GO:0019901 | 3.44 |
GTPase regulator activity | GO:0030695 | 4.01 |
Rho GTPase binding | GO:0017048 | 5.36 |
monocarboxylic acid binding | GO:0033293 | 5.61 |
nucleoside-triphosphatase regulator activity | GO:0060589 | 3.92 |
kinase binding | GO:0019900 | 3.32 |
carboxylic acid binding | GO:0031406 | 4.64 |
protein binding | GO:0005515 | 0.46 |
enzyme activator activity | GO:0008047 | 3.56 |