Gene table of ATP1A2 : ATPase Na+/K+ transporting subunit alpha 2

Gene-disease associations table

Disease IDDisease nameSource of annotation with ATP1A2OMIM linkNumber of associated genesgenes
PS104290ALTERNATING HEMIPLEGIA OF CHILDHOODClinVar, OMIM, HUMSAVAR link to OMIM 2ATP1A2, ATP1A3
602481MIGRAINE, FAMILIAL HEMIPLEGIC, 2ClinVar, OMIM, HUMSAVAR link to OMIM 1ATP1A2

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Annotation of the gene ATP1A2

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Salivary secretionhsa049706.23
Gastric acid secretionhsa049716.48
Endocrine and other factor-regulated calcium reabsorptionhsa049617.12
Aldosterone-regulated sodium reabsorptionhsa049607.41
Protein digestion and absorptionhsa049746.2
Bile secretionhsa049766.56
Carbohydrate digestion and absorptionhsa049737.28
cGMP-PKG signaling pathwayhsa040225.32
Proximal tubule bicarbonate reclamationhsa049648.24
Pancreatic secretionhsa049726.07
cAMP signaling pathwayhsa040245.05
Mineral absorptionhsa049787.09
Insulin secretionhsa049116.18
Thyroid hormone synthesishsa049186.56
Thyroid hormone signaling pathwayhsa049195.82
Cardiac muscle contractionhsa042606.34
Adrenergic signaling in cardiomyocyteshsa042615.44
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Ion channel transportR-HSA-9837125.34
Ion transport by P-type ATPasesR-HSA-9368377.46
Transmembrane transport of small moleculesR-HSA-3825513.79
Associated GO terms for Molecular function
GO termGO IDGO IC
purine ribonucleoside triphosphate bindingGO:00356392.22
drug bindingGO:00081445.03
bindingGO:00054880.18
ATPase activityGO:00168873.65
nucleotide bindingGO:00001661.96
heterocyclic compound bindingGO:19013631.06
purine nucleoside bindingGO:00018832.22
nucleoside bindingGO:00018822.21
cation bindingGO:00431691.4
potassium ion bindingGO:00309557.03
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesGO:00168205.03
sodium ion transmembrane transporter activityGO:00150814.83
ATPase activity, coupledGO:00426233.97
chaperone bindingGO:00510875.34
transmembrane transporter activityGO:00228572.82
ion bindingGO:00431671.36
sodium:potassium-exchanging ATPase activityGO:00053917.44
primary active transmembrane transporter activityGO:00153994.98
nucleoside phosphate bindingGO:19012651.96
ribonucleoside bindingGO:00325492.22
purine nucleotide bindingGO:00170762.19
metal ion transmembrane transporter activityGO:00468733.71
metal ion bindingGO:00468721.41
active transmembrane transporter activityGO:00228043.85
hydrolase activityGO:00167871.9
active ion transmembrane transporter activityGO:00228535.06
ATPase coupled ion transmembrane transporter activityGO:00426255.46
transporter activityGO:00052152.57
cation transmembrane transporter activityGO:00083243.32
nucleoside-triphosphatase activityGO:00171113.09
lipid bindingGO:00082893.26
small molecule bindingGO:00360941.89
catalytic activityGO:00038241.05
steroid bindingGO:00054965.24
steroid hormone bindingGO:19902397.95
hormone bindingGO:00425625.53
potassium-transporting ATPase activityGO:00085567.34
substrate-specific transmembrane transporter activityGO:00228912.9
inorganic cation transmembrane transporter activityGO:00228903.49
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:00168183.03
substrate-specific transporter activityGO:00228922.72
adenyl nucleotide bindingGO:00305542.4
carbohydrate derivative bindingGO:00973672.03
organic cyclic compound bindingGO:00971591.05
ATPase activity, coupled to movement of substancesGO:00434924.93
alkali metal ion bindingGO:00314206.69
sodium ion bindingGO:00314027.1
hydrolase activity, acting on acid anhydridesGO:00168173.03
cation-transporting ATPase activityGO:00198295.64
ion transmembrane transporter activityGO:00150753.04
pyrophosphatase activityGO:00164623.04
monovalent inorganic cation transmembrane transporter activityGO:00150773.87
purine ribonucleoside bindingGO:00325502.22
adenyl ribonucleotide bindingGO:00325592.41
ATP bindingGO:00055242.43
protein bindingGO:00055150.46
ATPase activity, coupled to transmembrane movement of substancesGO:00426265.06
purine ribonucleotide bindingGO:00325552.2
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanismGO:00156626.24
potassium ion transmembrane transporter activityGO:00150794.77
P-P-bond-hydrolysis-driven transmembrane transporter activityGO:00154054.98
ribonucleotide bindingGO:00325532.19