| Disease ID | Disease name | Source of annotation with AVP | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 125700 | DIABETES INSIPIDUS, NEUROHYPOPHYSEAL | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | AVP |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Vasopressin-regulated water reabsorption | hsa04962 | 7.18 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Circadian Clock | R-HSA-400253 | 7.03 |
| Vasopressin-like receptors | R-HSA-388479 | 10.4 |
| GPCR ligand binding | R-HSA-500792 | 4.19 |
| Signaling by GPCR | R-HSA-372790 | 2.68 |
| GPCR downstream signaling | R-HSA-388396 | 3.07 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
| Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 4.26 |
| BMAL1:CLOCK,NPAS2 activates circadian gene expression | R-HSA-1368108 | 7.59 |
| G alpha (q) signalling events | R-HSA-416476 | 5.42 |
| SLC-mediated transmembrane transport | R-HSA-425407 | 4.95 |
| G alpha (s) signalling events | R-HSA-418555 | 5.99 |
| Transmembrane transport of small molecules | R-HSA-382551 | 3.79 |
| Peptide ligand-binding receptors | R-HSA-375276 | 5.41 |
| Aquaporin-mediated transport | R-HSA-445717 | 7.31 |
| Transport of vitamins, nucleosides, and related molecules | R-HSA-425397 | 7.73 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 7.56 |
| Transport of organic anions | R-HSA-879518 | 9.52 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| peptidase inhibitor activity | GO:0030414 | 4.55 |
| binding | GO:0005488 | 0.18 |
| signal transducer activity | GO:0004871 | 2.28 |
| G-protein coupled receptor binding | GO:0001664 | 4.18 |
| enzyme inhibitor activity | GO:0004857 | 3.78 |
| molecular function regulator | GO:0098772 | 2.51 |
| cysteine-type endopeptidase regulator activity involved in apoptotic process | GO:0043028 | 6.02 |
| transferase activity | GO:0016740 | 1.95 |
| protein kinase activity | GO:0004672 | 3.27 |
| endopeptidase regulator activity | GO:0061135 | 4.57 |
| cysteine-type endopeptidase inhibitor activity involved in apoptotic process | GO:0043027 | 6.6 |
| hormone activity | GO:0005179 | 4.95 |
| peptidase regulator activity | GO:0061134 | 4.37 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| kinase activity | GO:0016301 | 2.93 |
| catalytic activity | GO:0003824 | 1.05 |
| endopeptidase inhibitor activity | GO:0004866 | 4.6 |
| cysteine-type endopeptidase inhibitor activity | GO:0004869 | 5.71 |
| neuropeptide hormone activity | GO:0005184 | 6.34 |
| neurohypophyseal hormone activity | GO:0005185 | 9.05 |
| V1B vasopressin receptor binding | GO:0031895 | 9.74 |
| V1A vasopressin receptor binding | GO:0031894 | 9.05 |
| vasopressin receptor binding | GO:0031893 | 8.64 |
| phosphotransferase activity, alcohol group as acceptor | GO:0016773 | 3.08 |
| protein binding | GO:0005515 | 0.46 |
| transferase activity, transferring phosphorus-containing groups | GO:0016772 | 2.77 |
| receptor binding | GO:0005102 | 2.43 |