| Disease ID | Disease name | Source of annotation with AVPR2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 300539 | NEPHROGENIC SYNDROME OF INAPPROPRIATE ANTIDIURESIS | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | AVPR2 |
| 304800 | DIABETES INSIPIDUS, NEPHROGENIC, X-LINKED | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | AVPR2 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Vasopressin-regulated water reabsorption | hsa04962 | 7.18 |
| Neuroactive ligand-receptor interaction | hsa04080 | 4.58 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| GPCR ligand binding | R-HSA-500792 | 4.19 |
| Signaling by GPCR | R-HSA-372790 | 2.68 |
| GPCR downstream signaling | R-HSA-388396 | 3.07 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
| Vasopressin-like receptors | R-HSA-388479 | 10.4 |
| Transmembrane transport of small molecules | R-HSA-382551 | 3.79 |
| Aquaporin-mediated transport | R-HSA-445717 | 7.31 |
| Peptide ligand-binding receptors | R-HSA-375276 | 5.41 |
| Vasopressin regulates renal water homeostasis via Aquaporins | R-HSA-432040 | 7.56 |
| G alpha (s) signalling events | R-HSA-418555 | 5.99 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| G-protein coupled peptide receptor activity | GO:0008528 | 4.86 |
| G-protein coupled receptor activity | GO:0004930 | 2.95 |
| signaling receptor activity | GO:0038023 | 2.49 |
| protein binding | GO:0005515 | 0.46 |
| vasopressin receptor activity | GO:0005000 | 7.79 |
| amide binding | GO:0033218 | 4.14 |
| molecular transducer activity | GO:0060089 | 2.32 |
| transmembrane signaling receptor activity | GO:0004888 | 2.57 |
| peptide receptor activity | GO:0001653 | 4.84 |
| receptor activity | GO:0004872 | 2.32 |
| signal transducer activity | GO:0004871 | 2.28 |
| peptide binding | GO:0042277 | 4.22 |
| transmembrane receptor activity | GO:0099600 | 2.53 |
| binding | GO:0005488 | 0.18 |