| Disease ID | Disease name | Source of annotation with BAG3 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS115200 | DILATED CARDIOMYOPATHY | ClinVar, OMIM, HUMSAVAR | link to OMIM | 36 | MYBPC3, VCL, PSEN2, PLN, LDB3, ACTC1, BAG3, RBM20, CSRP3, RAF1, MYH7, SGCD, TTN, FKTN, CRYAB, NEXN, SDHA, ABCC9, DSG2, ACTN2, TNNT2, GATAD1, EYA4, TNNC1, LAMA4, SCN5A, MYH6, DMD, TPM1, TNNI3, PRDM16, DES, LMNA, TMPO, MYPN, PSEN1 |
| PS601419 | MYOFIBRILLAR MYOPATHY | ClinVar, OMIM, HUMSAVAR | link to OMIM | 7 | CRYAB, FLNC, DES, MYOT, LDB3, DNAJB6, BAG3 |
Download the gene annotation in CSV format
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Cellular response to heat stress | R-HSA-3371556 | 6.59 |
| Cellular responses to stress | R-HSA-2262752 | 4.56 |
| Regulation of HSF1-mediated heat shock response | R-HSA-3371453 | 6.94 |
| GO term | GO ID | GO IC |
|---|---|---|
| ATPase regulator activity | GO:0060590 | 6.34 |
| adenyl nucleotide binding | GO:0030554 | 2.4 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| chaperone binding | GO:0051087 | 5.34 |
| adenyl-nucleotide exchange factor activity | GO:0000774 | 7.44 |
| nucleotide binding | GO:0000166 | 1.96 |
| small molecule binding | GO:0036094 | 1.89 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| protein complex binding | GO:0032403 | 3.09 |
| purine nucleotide binding | GO:0017076 | 2.19 |
| molecular function regulator | GO:0098772 | 2.51 |
| nucleoside-triphosphatase regulator activity | GO:0060589 | 3.92 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| nucleoside phosphate binding | GO:1901265 | 1.96 |