| Disease ID | Disease name | Source of annotation with BAX | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 114500 | COLORECTAL CANCER | OMIM | link to OMIM | 30 | TLR4, RAD54B, PTPRJ, TP53, EP300, PTPN12, ODC1, FLCN, TLR2, BAX, PLA2G2A, AURKA, NRAS, APC, MCC, TRIM28, MLH3, AKT1, MT-CO1, AXIN2, CTNNB1, PDGFRL, PIK3CA, KAT5, DCC, BRAF, CCND1, FGFR3, DLC1, BUB1B |
| 613065 | LEUKEMIA, ACUTE LYMPHOBLASTIC | OMIM | link to OMIM | 9 | PAX5, BCR, BAX, FLT3, NBN, TAL2, TAL1, NUP214, TCF3 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Colorectal cancer | hsa05210 | 6.52 |
| Pathways in cancer | hsa05200 | 3.98 |
| Viral carcinogenesis | hsa05203 | 5.08 |
| p53 signaling pathway | hsa04115 | 6.56 |
| Protein processing in endoplasmic reticulum | hsa04141 | 5.35 |
| Neurotrophin signaling pathway | hsa04722 | 5.78 |
| Prion diseases | hsa05020 | 7.48 |
| HTLV-I infection | hsa05166 | 4.59 |
| Tuberculosis | hsa05152 | 5.17 |
| Amyotrophic lateral sclerosis (ALS) | hsa05014 | 7.01 |
| Apoptosis | hsa04210 | 6.23 |
| Huntington's disease | hsa05016 | 5.17 |
| Hepatitis B | hsa05161 | 5.52 |
| Non-alcoholic fatty liver disease (NAFLD) | hsa04932 | 5.51 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Activation, translocation and oligomerization of BAX | R-HSA-114294 | 11.98 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 7.73 |
| Programmed Cell Death | R-HSA-5357801 | 5.65 |
| Apoptosis | R-HSA-109581 | 5.68 |
| GO term | GO ID | GO IC |
|---|---|---|
| death domain binding | GO:0070513 | 7.54 |
| heat shock protein binding | GO:0031072 | 5.24 |
| transporter activity | GO:0005215 | 2.57 |
| chaperone binding | GO:0051087 | 5.34 |
| lipid binding | GO:0008289 | 3.26 |
| BH domain binding | GO:0051400 | 7.66 |
| protein homodimerization activity | GO:0042803 | 3.16 |
| transmembrane transporter activity | GO:0022857 | 2.82 |
| channel activity | GO:0015267 | 3.6 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| BH3 domain binding | GO:0051434 | 8.35 |
| protein complex binding | GO:0032403 | 3.09 |
| passive transmembrane transporter activity | GO:0022803 | 3.6 |
| protein dimerization activity | GO:0046983 | 2.72 |
| protein heterodimerization activity | GO:0046982 | 3.64 |
| identical protein binding | GO:0042802 | 2.63 |
| protein domain specific binding | GO:0019904 | 3.32 |