Gene table of BAX : BCL2 associated X, apoptosis regulator

Gene-disease associations table

Disease IDDisease nameSource of annotation with BAXOMIM linkNumber of associated genesgenes
114500COLORECTAL CANCEROMIM link to OMIM 30TLR4, RAD54B, PTPRJ, TP53, EP300, PTPN12, ODC1, FLCN, TLR2, BAX, PLA2G2A, AURKA, NRAS, APC, MCC, TRIM28, MLH3, AKT1, MT-CO1, AXIN2, CTNNB1, PDGFRL, PIK3CA, KAT5, DCC, BRAF, CCND1, FGFR3, DLC1, BUB1B
613065LEUKEMIA, ACUTE LYMPHOBLASTICOMIM link to OMIM 9PAX5, BCR, BAX, FLT3, NBN, TAL2, TAL1, NUP214, TCF3

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Annotation of the gene BAX

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Colorectal cancerhsa052106.52
Pathways in cancerhsa052003.98
Viral carcinogenesishsa052035.08
p53 signaling pathwayhsa041156.56
Protein processing in endoplasmic reticulumhsa041415.35
Neurotrophin signaling pathwayhsa047225.78
Prion diseaseshsa050207.48
HTLV-I infectionhsa051664.59
Tuberculosishsa051525.17
Amyotrophic lateral sclerosis (ALS)hsa050147.01
Apoptosishsa042106.23
Huntington's diseasehsa050165.17
Hepatitis Bhsa051615.52
Non-alcoholic fatty liver disease (NAFLD)hsa049325.51
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Activation, translocation and oligomerization of BAXR-HSA-11429411.98
Intrinsic Pathway for ApoptosisR-HSA-1096067.73
Programmed Cell DeathR-HSA-53578015.65
ApoptosisR-HSA-1095815.68
Associated GO terms for Molecular function
GO termGO IDGO IC
death domain bindingGO:00705137.54
heat shock protein bindingGO:00310725.24
transporter activityGO:00052152.57
chaperone bindingGO:00510875.34
lipid bindingGO:00082893.26
BH domain bindingGO:00514007.66
protein homodimerization activityGO:00428033.16
transmembrane transporter activityGO:00228572.82
channel activityGO:00152673.6
macromolecular complex bindingGO:00448772.61
bindingGO:00054880.18
protein bindingGO:00055150.46
BH3 domain bindingGO:00514348.35
protein complex bindingGO:00324033.09
passive transmembrane transporter activityGO:00228033.6
protein dimerization activityGO:00469832.72
protein heterodimerization activityGO:00469823.64
identical protein bindingGO:00428022.63
protein domain specific bindingGO:00199043.32