Gene table of CARD11 : caspase recruitment domain family member 11

Gene-disease associations table

Disease IDDisease nameSource of annotation with CARD11OMIM linkNumber of associated genesgenes
616452B-CELL EXPANSION WITH NFKB AND T-CELL ANERGYClinVar, OMIM, HUMSAVAR link to OMIM 1CARD11
615206IMMUNODEFICIENCY 11ClinVar, OMIM link to OMIM 1CARD11

Download the gene annotation in CSV format

Annotation of the gene CARD11

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
T cell receptor signaling pathwayhsa046606.01
NF-kappa B signaling pathwayhsa040646.21
B cell receptor signaling pathwayhsa046626.52
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
C-type lectin receptors (CLRs)R-HSA-56214816.06
Downstream TCR signalingR-HSA-2024247.01
Fc epsilon receptor (FCERI) signalingR-HSA-24542024.03
Innate Immune SystemR-HSA-1682493.17
Immune SystemR-HSA-1682562.37
Signaling by the B Cell Receptor (BCR)R-HSA-9837054.62
Adaptive Immune SystemR-HSA-12802183.19
CLEC7A (Dectin-1) signalingR-HSA-56077646.38
Downstream signaling events of B Cell Receptor (BCR)R-HSA-11683725.59
Activation of NF-kappaB in B cellsR-HSA-11690916.94
TCR signalingR-HSA-2024036.64
FCERI mediated NF-kB activationR-HSA-28718375.11
Associated GO terms for Molecular function
GO termGO IDGO IC
guanylate kinase activityGO:00043857.25
nucleotide kinase activityGO:00192016.52
nucleobase-containing compound kinase activityGO:00192055.85
transferase activity, transferring phosphorus-containing groupsGO:00167722.77
kinase activityGO:00163012.93
CARD domain bindingGO:00507007.66
phosphotransferase activity, phosphate group as acceptorGO:00167766.02
catalytic activityGO:00038241.05
transferase activityGO:00167401.95
bindingGO:00054880.18
protein bindingGO:00055150.46
protein domain specific bindingGO:00199043.32