Disease ID | Disease name | Source of annotation with CCR5 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
610379 | WEST NILE VIRUS, SUSCEPTIBILITY TO | OMIM | link to OMIM | 1 | CCR5 |
612522 | DIABETES MELLITUS, INSULIN-DEPENDENT, 22 | OMIM | link to OMIM | 1 | CCR5 |
609532 | HEPATITIS C VIRUS, SUSCEPTIBILITY TO | OMIM | link to OMIM | 6 | IFNG, PTPRC, IFNL3, KRT8, KRT18, CCR5 |
609423 | HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO | ClinVar, OMIM | link to OMIM | 16 | HLA-C, IFNG, CCL3, CD209, IL4R, KIR3DL1, CCL2, TLR3, CCR2, CX3CR1, CCL11, CCR5, CXCL12, CCL3L1, CXCR1, IL10 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Viral carcinogenesis | hsa05203 | 5.08 |
Chemokine signaling pathway | hsa04062 | 5.19 |
Endocytosis | hsa04144 | 4.92 |
Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
Toxoplasmosis | hsa05145 | 5.71 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Infectious disease | R-HSA-5663205 | 4.47 |
Binding and entry of HIV virion | R-HSA-173107 | 10.98 |
GPCR ligand binding | R-HSA-500792 | 4.19 |
Signaling by GPCR | R-HSA-372790 | 2.68 |
G alpha (i) signalling events | R-HSA-418594 | 5.1 |
Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
HIV Infection | R-HSA-162906 | 5.22 |
Peptide ligand-binding receptors | R-HSA-375276 | 5.41 |
Chemokine receptors bind chemokines | R-HSA-380108 | 7.2 |
GPCR downstream signaling | R-HSA-388396 | 3.07 |
Signal Transduction | R-HSA-162582 | 1.78 |
Early Phase of HIV Life Cycle | R-HSA-162594 | 9.4 |
Disease | R-HSA-1643685 | 3.33 |
HIV Life Cycle | R-HSA-162587 | 5.89 |
GO term | GO ID | GO IC |
---|---|---|
signaling receptor activity | GO:0038023 | 2.49 |
chemokine binding | GO:0019956 | 6.69 |
C-C chemokine binding | GO:0019957 | 7.79 |
cytokine binding | GO:0019955 | 5.21 |
chemokine receptor activity | GO:0004950 | 6.52 |
molecular transducer activity | GO:0060089 | 2.32 |
receptor activity | GO:0004872 | 2.32 |
signal transducer activity | GO:0004871 | 2.28 |
C-C chemokine receptor activity | GO:0016493 | 7.25 |
G-protein coupled peptide receptor activity | GO:0008528 | 4.86 |
G-protein coupled receptor activity | GO:0004930 | 2.95 |
phosphoric diester hydrolase activity | GO:0008081 | 5.23 |
actin binding | GO:0003779 | 3.74 |
coreceptor activity | GO:0015026 | 6.1 |
cytokine receptor activity | GO:0004896 | 5.24 |
hydrolase activity | GO:0016787 | 1.9 |
hydrolase activity, acting on ester bonds | GO:0016788 | 3.1 |
catalytic activity | GO:0003824 | 1.05 |
peptide receptor activity | GO:0001653 | 4.84 |
chemokine (C-C motif) ligand 5 binding | GO:0071791 | 8.64 |
phosphoric ester hydrolase activity | GO:0042578 | 3.82 |
phosphatidylinositol phospholipase C activity | GO:0004435 | 6.41 |
G-protein coupled chemoattractant receptor activity | GO:0001637 | 6.52 |
cytoskeletal protein binding | GO:0008092 | 3.02 |
virus receptor activity | GO:0001618 | 5.49 |
transmembrane signaling receptor activity | GO:0004888 | 2.57 |
phospholipase C activity | GO:0004629 | 6.3 |
protein binding | GO:0005515 | 0.46 |
phospholipase activity | GO:0004620 | 5.16 |
lipase activity | GO:0016298 | 4.96 |
transmembrane receptor activity | GO:0099600 | 2.53 |
binding | GO:0005488 | 0.18 |