Gene table of CD27 : CD27 molecule

Gene-disease associations table

Disease ID	Disease name	Source of annotation with CD27	OMIM link	Number of associated genes	genes
PS308240	LYMPHOPROLIFERATIVE SYNDROME	ClinVar, OMIM, HUMSAVAR	link to OMIM	4	ITK, SH2D1A, CD27, XIAP

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Cytokine-cytokine receptor interaction	hsa04060	4.67

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Cytokine Signaling in Immune system	R-HSA-1280215	3.74
TNFs bind their physiological receptors	R-HSA-5669034	8.34
TNFR2 non-canonical NF-kB pathway	R-HSA-5668541	6.4
Immune System	R-HSA-168256	2.37

Associated GO terms for Molecular function

GO term	GO ID	GO IC
binding	GO:0005488	0.18
peptidase inhibitor activity	GO:0030414	4.55
signaling receptor activity	GO:0038023	2.49
protein binding	GO:0005515	0.46
endopeptidase inhibitor activity	GO:0004866	4.6
cysteine-type endopeptidase regulator activity involved in apoptotic process	GO:0043028	6.02
enzyme regulator activity	GO:0030234	2.85
peptidase regulator activity	GO:0061134	4.37
death receptor activity	GO:0005035	6.56
transmembrane signaling receptor activity	GO:0004888	2.57
transmembrane receptor activity	GO:0099600	2.53
tumor necrosis factor-activated receptor activity	GO:0005031	6.56
signal transducer activity	GO:0004871	2.28
cysteine-type endopeptidase inhibitor activity	GO:0004869	5.71
enzyme inhibitor activity	GO:0004857	3.78
molecular function regulator	GO:0098772	2.51
molecular transducer activity	GO:0060089	2.32
endopeptidase regulator activity	GO:0061135	4.57
cysteine-type endopeptidase inhibitor activity involved in apoptotic process	GO:0043027	6.6
receptor activity	GO:0004872	2.32