Disease ID | Disease name | Source of annotation with CD40LG | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS308230 | IMMUNODEFICIENCY WITH HYPER-IGM | ClinVar, OMIM, HUMSAVAR | link to OMIM | 4 | AICDA, CD40LG, UNG, CD40 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Systemic lupus erythematosus | hsa05322 | 5.95 |
Autoimmune thyroid disease | hsa05320 | 6.62 |
Asthma | hsa05310 | 7.34 |
Allograft rejection | hsa05330 | 6.91 |
T cell receptor signaling pathway | hsa04660 | 6.01 |
Intestinal immune network for IgA production | hsa04672 | 6.79 |
Cell adhesion molecules (CAMs) | hsa04514 | 5.36 |
Viral myocarditis | hsa05416 | 6.45 |
Malaria | hsa05144 | 7.15 |
Toxoplasmosis | hsa05145 | 5.71 |
Primary immunodeficiency | hsa05340 | 7.52 |
NF-kappa B signaling pathway | hsa04064 | 6.21 |
Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 6.4 |
Immune System | R-HSA-168256 | 2.37 |
Cytokine Signaling in Immune system | R-HSA-1280215 | 3.74 |
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 8.89 |
Adaptive Immune System | R-HSA-1280218 | 3.19 |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 4.7 |
GO term | GO ID | GO IC |
---|---|---|
cytokine receptor binding | GO:0005126 | 4.14 |
tumor necrosis factor receptor superfamily binding | GO:0032813 | 5.89 |
CD40 receptor binding | GO:0005174 | 9.05 |
tumor necrosis factor receptor binding | GO:0005164 | 6.3 |
cytokine activity | GO:0005125 | 4.34 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
receptor binding | GO:0005102 | 2.43 |