Disease ID | Disease name | Source of annotation with CD46 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS235400 | HEMOLYTIC UREMIC SYNDROME | ClinVar, OMIM, HUMSAVAR | link to OMIM | 11 | CFH, CFHR3, CFHR1, BAAT, CFI, THBD, C3AR1, C3, CD46, CFB, DGKE |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Complement and coagulation cascades | hsa04610 | 6.58 |
Measles | hsa05162 | 5.6 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Complement cascade | R-HSA-166658 | 5.38 |
Innate Immune System | R-HSA-168249 | 3.17 |
Regulation of Complement cascade | R-HSA-977606 | 8.4 |
Immune System | R-HSA-168256 | 2.37 |
GO term | GO ID | GO IC |
---|---|---|
hydrolase activity | GO:0016787 | 1.9 |
endopeptidase activity | GO:0004175 | 3.63 |
molecular transducer activity | GO:0060089 | 2.32 |
complement binding | GO:0001848 | 6.79 |
enzyme regulator activity | GO:0030234 | 2.85 |
virus receptor activity | GO:0001618 | 5.49 |
cadherin binding | GO:0045296 | 6.41 |
catalytic activity | GO:0003824 | 1.05 |
cell adhesion molecule binding | GO:0050839 | 4.5 |
peptidase activity, acting on L-amino acid peptides | GO:0070011 | 3.26 |
receptor activity | GO:0004872 | 2.32 |
protein binding | GO:0005515 | 0.46 |
enzyme inhibitor activity | GO:0004857 | 3.78 |
molecular function regulator | GO:0098772 | 2.51 |
peptidase activity | GO:0008233 | 3.23 |
binding | GO:0005488 | 0.18 |