Gene table of CDK5 : cyclin dependent kinase 5

Gene-disease associations table

Disease ID	Disease name	Source of annotation with CDK5	OMIM link	Number of associated genes	genes
PS607432	LISSENCEPHALY	ClinVar, OMIM	link to OMIM	9	CDK5, APOC3, PAFAH1B1, ARX, DCX, LAMB1, TUBA1A, RELN, KATNB1

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Annotation of the gene CDK5

Associated genes in ENSEMBL

ENSG00000164885

Associated proteins - SwissProt Accession ID

Q00535

Associated PDB IDs

Cytogenetic Band

7q36.1

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Axon guidance	hsa04360	5.63
Cocaine addiction	hsa05030	7.07
Alzheimer's disease	hsa05010	5.34

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
DARPP-32 events	R-HSA-180024	8.4
Signaling by GPCR	R-HSA-372790	2.68
CRMPs in Sema3A signaling	R-HSA-399956	8.98
Opioid Signalling	R-HSA-111885	6.64
Signal Transduction	R-HSA-162582	1.78
Semaphorin interactions	R-HSA-373755	6.92
Axon guidance	R-HSA-422475	3.93
Factors involved in megakaryocyte development and platelet production	R-HSA-983231	5.88
Hemostasis	R-HSA-109582	3.98
Developmental Biology	R-HSA-1266738	3.48

Associated GO terms for Molecular function

GO term	GO ID	GO IC
purine ribonucleoside triphosphate binding	GO:0035639	2.22
enzyme binding	GO:0019899	2.27
binding	GO:0005488	0.18
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	6.21
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
nucleoside binding	GO:0001882	2.21
molecular function regulator	GO:0098772	2.51
acetylcholine receptor regulator activity	GO:0030548	8.64
acetylcholine receptor activator activity	GO:0030549	9.74
protein serine/threonine kinase activity	GO:0004674	3.64
receptor regulator activity	GO:0030545	5.91
receptor activator activity	GO:0030546	6.27
nucleotide binding	GO:0000166	1.96
cyclin-dependent protein kinase activity	GO:0097472	6.21
transferase activity	GO:0016740	1.95
purine nucleoside binding	GO:0001883	2.22
protein kinase activity	GO:0004672	3.27
purine nucleotide binding	GO:0017076	2.19
ephrin receptor binding	GO:0046875	6.56
ATP binding	GO:0005524	2.43
kinase activity	GO:0016301	2.93
ribonucleoside binding	GO:0032549	2.22
ErbB-2 class receptor binding	GO:0005176	8.13
protein kinase binding	GO:0019901	3.44
kinase binding	GO:0019900	3.32
ErbB-3 class receptor binding	GO:0043125	8.35
small molecule binding	GO:0036094	1.89
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
catalytic activity	GO:0003824	1.05
cytoskeletal protein binding	GO:0008092	3.02
p53 binding	GO:0002039	5.53
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
adenyl ribonucleotide binding	GO:0032559	2.41
protein binding	GO:0005515	0.46
tau-protein kinase activity	GO:0050321	7.25
purine ribonucleotide binding	GO:0032555	2.2
receptor binding	GO:0005102	2.43
neurotransmitter receptor regulator activity	GO:0099602	8.64
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19