| Disease ID | Disease name | Source of annotation with CLDN16 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS602014 | HYPOMAGNESEMIA | ClinVar, OMIM, HUMSAVAR | link to OMIM | 6 | CLDN19, CLDN16, TRPM6, EGF, CNNM2, FXYD2 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Tight junction | hsa04530 | 5.53 |
| Cell adhesion molecules (CAMs) | hsa04514 | 5.36 |
| Leukocyte transendothelial migration | hsa04670 | 5.74 |
| Hepatitis C | hsa05160 | 5.68 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Cell-Cell communication | R-HSA-1500931 | 5.87 |
| Cell-cell junction organization | R-HSA-421270 | 7.03 |
| Tight junction interactions | R-HSA-420029 | 8.08 |
| Cell junction organization | R-HSA-446728 | 6.51 |
| GO term | GO ID | GO IC |
|---|---|---|
| substrate-specific transmembrane transporter activity | GO:0022891 | 2.9 |
| inorganic cation transmembrane transporter activity | GO:0022890 | 3.49 |
| substrate-specific transporter activity | GO:0022892 | 2.72 |
| transporter activity | GO:0005215 | 2.57 |
| cation transmembrane transporter activity | GO:0008324 | 3.32 |
| divalent inorganic cation transmembrane transporter activity | GO:0072509 | 4.62 |
| ion transmembrane transporter activity | GO:0015075 | 3.04 |
| transmembrane transporter activity | GO:0022857 | 2.82 |
| magnesium ion transmembrane transporter activity | GO:0015095 | 6.97 |
| protein binding | GO:0005515 | 0.46 |
| metal ion transmembrane transporter activity | GO:0046873 | 3.71 |
| structural molecule activity | GO:0005198 | 3.1 |
| identical protein binding | GO:0042802 | 2.63 |
| binding | GO:0005488 | 0.18 |