Gene table of CR2 : complement C3d receptor 2

Gene-disease associations table

Disease ID	Disease name	Source of annotation with CR2	OMIM link	Number of associated genes	genes
610927	SYSTEMIC LUPUS ERYTHEMATOSUS, SUSCEPTIBILITY TO, 9	ClinVar, OMIM	link to OMIM	1	CR2
PS607594	IMMUNODEFICIENCY, COMMON VARIABLE	ClinVar, OMIM	link to OMIM	12	NFKB1, CD19, IL21, CR2, MS4A1, LRBA, NFKB2, CD81, IKZF1, TNFRSF13C, TNFRSF13B, ICOS

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
B cell receptor signaling pathway	hsa04662	6.52
Complement and coagulation cascades	hsa04610	6.58
Hematopoietic cell lineage	hsa04640	6.18
Epstein-Barr virus infection	hsa05169	4.97

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
signaling receptor activity	GO:0038023	2.49
nucleic acid binding	GO:0003676	1.44
complement binding	GO:0001848	6.79
organic cyclic compound binding	GO:0097159	1.05
virus receptor activity	GO:0001618	5.49
transmembrane signaling receptor activity	GO:0004888	2.57
signal transducer activity	GO:0004871	2.28
molecular transducer activity	GO:0060089	2.32
complement receptor activity	GO:0004875	8.35
transmembrane receptor activity	GO:0099600	2.53
receptor activity	GO:0004872	2.32
protein binding	GO:0005515	0.46
DNA binding	GO:0003677	1.92
protein dimerization activity	GO:0046983	2.72
protein homodimerization activity	GO:0042803	3.16
heterocyclic compound binding	GO:1901363	1.06
identical protein binding	GO:0042802	2.63
binding	GO:0005488	0.18