Gene table of CRB2 : crumbs 2, cell polarity complex component

Gene-disease associations table

Disease ID	Disease name	Source of annotation with CRB2	OMIM link	Number of associated genes	genes
219730	VENTRICULOMEGALY WITH CYSTIC KIDNEY DISEASE	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	CRB2
PS603278	FOCAL SEGMENTAL GLOMERULOSCLEROSIS	ClinVar, OMIM, HUMSAVAR	link to OMIM	9	ACTN4, ANLN, INF2, TRPC6, PAX2, CD2AP, CRB2, MYO1E, APOL1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Hippo signaling pathway	hsa04390	5.37

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
cation binding	GO:0043169	1.4
enzyme binding	GO:0019899	2.27
metal ion binding	GO:0046872	1.41
peptidase inhibitor activity	GO:0030414	4.55
protein binding	GO:0005515	0.46
enzyme regulator activity	GO:0030234	2.85
peptidase regulator activity	GO:0061134	4.37
aspartic-type endopeptidase inhibitor activity	GO:0019828	9.05
ion binding	GO:0043167	1.36
calcium ion binding	GO:0005509	3.17
endopeptidase inhibitor activity	GO:0004866	4.6
enzyme inhibitor activity	GO:0004857	3.78
molecular function regulator	GO:0098772	2.51
endopeptidase regulator activity	GO:0061135	4.57
binding	GO:0005488	0.18