Disease ID | Disease name | Source of annotation with CST3 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
105150 | CEREBRAL AMYLOID ANGIOPATHY, CST3-RELATED | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | CST3 |
PS603075 | MACULAR DEGENERATION, AGE-RELATED | ClinVar, OMIM, HUMSAVAR | link to OMIM | 19 | RAX2, CFB, ERCC6, TLR4, CFHR3, CFHR1, HMCN1, CFI, CFH, C3, HTRA1, ABCA4, CX3CR1, FBLN5, C2, APOE, CST3, ARMS2, C9 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Salivary secretion | hsa04970 | 6.23 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Amyloids | R-HSA-977225 | 7.37 |
Disease | R-HSA-1643685 | 3.33 |
GO term | GO ID | GO IC |
---|---|---|
beta-amyloid binding | GO:0001540 | 6.21 |
peptidase inhibitor activity | GO:0030414 | 4.55 |
peptide binding | GO:0042277 | 4.22 |
amide binding | GO:0033218 | 4.14 |
enzyme regulator activity | GO:0030234 | 2.85 |
peptidase regulator activity | GO:0061134 | 4.37 |
enzyme binding | GO:0019899 | 2.27 |
protease binding | GO:0002020 | 5.08 |
protein binding | GO:0005515 | 0.46 |
endopeptidase inhibitor activity | GO:0004866 | 4.6 |
cysteine-type endopeptidase inhibitor activity | GO:0004869 | 5.71 |
enzyme inhibitor activity | GO:0004857 | 3.78 |
molecular function regulator | GO:0098772 | 2.51 |
endopeptidase regulator activity | GO:0061135 | 4.57 |
identical protein binding | GO:0042802 | 2.63 |
binding | GO:0005488 | 0.18 |