Disease ID | Disease name | Source of annotation with CTLA4 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
601388 | DIABETES MELLITUS, INSULIN-DEPENDENT, 12 | OMIM | link to OMIM | 1 | CTLA4 |
152700 | SYSTEMIC LUPUS ERYTHEMATOSUS | OMIM | link to OMIM | 6 | FCGR2A, PTPN22, CTLA4, TREX1, FCGR2B, DNASE1 |
140300 | HASHIMOTO THYROIDITIS | OMIM | link to OMIM | 1 | CTLA4 |
616100 | AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE V | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | CTLA4 |
PS212750 | CELIAC DISEASE | ClinVar, OMIM | link to OMIM | 4 | CTLA4, MYO9B, HLA-DQB1, HLA-DQA1 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
T cell receptor signaling pathway | hsa04660 | 6.01 |
Rheumatoid arthritis | hsa05323 | 6.05 |
Cell adhesion molecules (CAMs) | hsa04514 | 5.36 |
Autoimmune thyroid disease | hsa05320 | 6.62 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Costimulation by the CD28 family | R-HSA-388841 | 6.56 |
Immune System | R-HSA-168256 | 2.37 |
Adaptive Immune System | R-HSA-1280218 | 3.19 |
CTLA4 inhibitory signaling | R-HSA-389513 | 8.52 |
GO term | GO ID | GO IC |
---|---|---|
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |