Gene table of CTLA4 : cytotoxic T-lymphocyte associated protein 4

Gene-disease associations table

Disease IDDisease nameSource of annotation with CTLA4OMIM linkNumber of associated genesgenes
601388DIABETES MELLITUS, INSULIN-DEPENDENT, 12OMIM link to OMIM 1CTLA4
152700SYSTEMIC LUPUS ERYTHEMATOSUSOMIM link to OMIM 6FCGR2A, PTPN22, CTLA4, TREX1, FCGR2B, DNASE1
140300HASHIMOTO THYROIDITISOMIM link to OMIM 1CTLA4
616100AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE VClinVar, OMIM, HUMSAVAR link to OMIM 1CTLA4
PS212750CELIAC DISEASEClinVar, OMIM link to OMIM 4CTLA4, MYO9B, HLA-DQB1, HLA-DQA1

Download the gene annotation in CSV format

Annotation of the gene CTLA4

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
T cell receptor signaling pathwayhsa046606.01
Rheumatoid arthritishsa053236.05
Cell adhesion molecules (CAMs)hsa045145.36
Autoimmune thyroid diseasehsa053206.62
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Costimulation by the CD28 familyR-HSA-3888416.56
Immune SystemR-HSA-1682562.37
Adaptive Immune SystemR-HSA-12802183.19
CTLA4 inhibitory signalingR-HSA-3895138.52
Associated GO terms for Molecular function
GO termGO IDGO IC
bindingGO:00054880.18
protein bindingGO:00055150.46