Disease ID | Disease name | Source of annotation with CUBN | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
261100 | MEGALOBLASTIC ANEMIA 1 | ClinVar, OMIM, HUMSAVAR | link to OMIM | 2 | CUBN, AMN |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Vitamin digestion and absorption | hsa04977 | 8.24 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Metabolism of water-soluble vitamins and cofactors | R-HSA-196849 | 6.54 |
Lipoprotein metabolism | R-HSA-174824 | 8.23 |
Metabolism of vitamins and cofactors | R-HSA-196854 | 6.54 |
Lipid digestion, mobilization, and transport | R-HSA-73923 | 7.2 |
Defects in cobalamin (B12) metabolism | R-HSA-3296469 | 9.28 |
Vitamin D (calciferol) metabolism | R-HSA-196791 | 10.18 |
Diseases of metabolism | R-HSA-5668914 | 6.57 |
Defective CUBN causes hereditary megaloblastic anemia 1 | R-HSA-3359463 | 11.4 |
Defective AMN causes hereditary megaloblastic anemia 1 | R-HSA-3359462 | 11.4 |
Metabolism | R-HSA-1430728 | 2.34 |
Metabolism of steroid hormones and vitamin D | R-HSA-196071 | 7.89 |
HDL-mediated lipid transport | R-HSA-194223 | 9.08 |
Metabolism of lipids and lipoproteins | R-HSA-556833 | 3.79 |
Defects in vitamin and cofactor metabolism | R-HSA-3296482 | 8.52 |
Cobalamin (Cbl, vitamin B12) transport and metabolism | R-HSA-196741 | 8.73 |
Disease | R-HSA-1643685 | 3.33 |
GO term | GO ID | GO IC |
---|---|---|
cobalamin binding | GO:0031419 | 7.54 |
cation binding | GO:0043169 | 1.4 |
metal ion binding | GO:0046872 | 1.41 |
calcium ion binding | GO:0005509 | 3.17 |
tetrapyrrole binding | GO:0046906 | 4.8 |
organic cyclic compound binding | GO:0097159 | 1.05 |
vitamin binding | GO:0019842 | 5.34 |
ion binding | GO:0043167 | 1.36 |
small molecule binding | GO:0036094 | 1.89 |
molecular transducer activity | GO:0060089 | 2.32 |
receptor activity | GO:0004872 | 2.32 |
protein binding | GO:0005515 | 0.46 |
transporter activity | GO:0005215 | 2.57 |
protein dimerization activity | GO:0046983 | 2.72 |
protein homodimerization activity | GO:0042803 | 3.16 |
heterocyclic compound binding | GO:1901363 | 1.06 |
identical protein binding | GO:0042802 | 2.63 |
binding | GO:0005488 | 0.18 |