| Disease ID | Disease name | Source of annotation with CYBA | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS306400 | GRANULOMATOUS DISEASE, CHRONIC | ClinVar, OMIM, HUMSAVAR | link to OMIM | 5 | CYBA, CYBB, NCF1, NCF2, NCF4 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Leishmaniasis | hsa05140 | 6.32 |
| Leukocyte transendothelial migration | hsa04670 | 5.74 |
| Phagosome | hsa04145 | 5.27 |
| Osteoclast differentiation | hsa04380 | 5.64 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Infectious disease | R-HSA-5663205 | 4.47 |
| VEGFA-VEGFR2 Pathway | R-HSA-4420097 | 4.7 |
| RHO GTPase Effectors | R-HSA-195258 | 4.94 |
| RHO GTPases Activate NADPH Oxidases | R-HSA-5668599 | 9.52 |
| Signaling by VEGF | R-HSA-194138 | 4.66 |
| Antigen processing-Cross presentation | R-HSA-1236975 | 5.88 |
| Cross-presentation of particulate exogenous antigens (phagosomes) | R-HSA-1236973 | 9.98 |
| Immune System | R-HSA-168256 | 2.37 |
| Signaling by Rho GTPases | R-HSA-194315 | 4.43 |
| Class I MHC mediated antigen processing & presentation | R-HSA-983169 | 4.65 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| Latent infection of Homo sapiens with Mycobacterium tuberculosis | R-HSA-1222352 | 7.89 |
| Phagosomal maturation (early endosomal stage) | R-HSA-1222556 | 7.89 |
| Adaptive Immune System | R-HSA-1280218 | 3.19 |
| Disease | R-HSA-1643685 | 3.33 |
| GO term | GO ID | GO IC |
|---|---|---|
| cation binding | GO:0043169 | 1.4 |
| metal ion binding | GO:0046872 | 1.41 |
| heme binding | GO:0020037 | 4.86 |
| oxidoreductase activity, acting on NAD(P)H | GO:0016651 | 5.13 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| protein heterodimerization activity | GO:0046982 | 3.64 |
| tetrapyrrole binding | GO:0046906 | 4.8 |
| superoxide-generating NADPH oxidase activity | GO:0016175 | 7.34 |
| SH3 domain binding | GO:0017124 | 4.98 |
| ion binding | GO:0043167 | 1.36 |
| catalytic activity | GO:0003824 | 1.05 |
| oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor | GO:0050664 | 6.97 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| protein dimerization activity | GO:0046983 | 2.72 |
| electron carrier activity | GO:0009055 | 4.97 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| protein domain specific binding | GO:0019904 | 3.32 |
| oxidoreductase activity | GO:0016491 | 3.12 |