| Disease ID | Disease name | Source of annotation with CYCS | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 612004 | THROMBOCYTOPENIA 4 | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | CYCS |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Hepatitis B | hsa05161 | 5.52 |
| Legionellosis | hsa05134 | 6.88 |
| Non-alcoholic fatty liver disease (NAFLD) | hsa04932 | 5.51 |
| Metabolic pathways | hsa01100 | 2.49 |
| Tuberculosis | hsa05152 | 5.17 |
| Pathways in cancer | hsa05200 | 3.98 |
| p53 signaling pathway | hsa04115 | 6.56 |
| Amyotrophic lateral sclerosis (ALS) | hsa05014 | 7.01 |
| Sulfur metabolism | hsa00920 | 9.45 |
| Herpes simplex infection | hsa05168 | 5.08 |
| Parkinson's disease | hsa05012 | 5.59 |
| Toxoplasmosis | hsa05145 | 5.71 |
| Influenza A | hsa05164 | 5.21 |
| Apoptosis | hsa04210 | 6.23 |
| Huntington's disease | hsa05016 | 5.17 |
| Alzheimer's disease | hsa05010 | 5.34 |
| Colorectal cancer | hsa05210 | 6.52 |
| Viral myocarditis | hsa05416 | 6.45 |
| Small cell lung cancer | hsa05222 | 6.17 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Transcriptional Regulation by TP53 | R-HSA-3700989 | 6.73 |
| Respiratory electron transport | R-HSA-611105 | 6.44 |
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | R-HSA-163200 | 6.12 |
| Generic Transcription Pathway | R-HSA-212436 | 3.86 |
| The citric acid (TCA) cycle and respiratory electron transport | R-HSA-1428517 | 5.71 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 4.63 |
| Activation of caspases through apoptosome-mediated cleavage | R-HSA-111459 | 10.66 |
| Cytochrome c-mediated apoptotic response | R-HSA-111461 | 10.66 |
| Cellular responses to stress | R-HSA-2262752 | 4.56 |
| Transcriptional activation of mitochondrial biogenesis | R-HSA-2151201 | 7.62 |
| Mitochondrial biogenesis | R-HSA-1592230 | 7.34 |
| Programmed Cell Death | R-HSA-5357801 | 5.65 |
| Apoptotic factor-mediated response | R-HSA-111471 | 10.18 |
| Metabolism | R-HSA-1430728 | 2.34 |
| Gene Expression | R-HSA-74160 | 2.72 |
| TP53 Regulates Metabolic Genes | R-HSA-5628897 | 6.73 |
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 8.23 |
| Formation of apoptosome | R-HSA-111458 | 11.4 |
| Intrinsic Pathway for Apoptosis | R-HSA-109606 | 7.73 |
| Apoptosis | R-HSA-109581 | 5.68 |
| Release of apoptotic factors from the mitochondria | R-HSA-111457 | 11.98 |
| GO term | GO ID | GO IC |
|---|---|---|
| phosphoprotein phosphatase activity | GO:0004721 | 4.55 |
| phosphatase activity | GO:0016791 | 4.11 |
| heme binding | GO:0020037 | 4.86 |
| tetrapyrrole binding | GO:0046906 | 4.8 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| hydrolase activity | GO:0016787 | 1.9 |
| protein serine/threonine phosphatase activity | GO:0004722 | 5.58 |
| hydrolase activity, acting on ester bonds | GO:0016788 | 3.1 |
| ion binding | GO:0043167 | 1.36 |
| phosphoric ester hydrolase activity | GO:0042578 | 3.82 |
| catalytic activity | GO:0003824 | 1.05 |
| cation binding | GO:0043169 | 1.4 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity | GO:0045155 | 9.05 |
| metal ion binding | GO:0046872 | 1.41 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| electron carrier activity | GO:0009055 | 4.97 |