Gene table of CYP2C9 : cytochrome P450 family 2 subfamily C member 9

Gene-disease associations table

Disease ID	Disease name	Source of annotation with CYP2C9	OMIM link	Number of associated genes	genes
122700	COUMARIN RESISTANCE	OMIM	link to OMIM	4	CYP2A6, F9, CYP2C9, VKORC1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Metabolism of xenobiotics by cytochrome P450	hsa00980	6.48
Chemical carcinogenesis	hsa05204	6.36
Drug metabolism - cytochrome P450	hsa00982	6.6
Retinol metabolism	hsa00830	6.79
Arachidonic acid metabolism	hsa00590	6.79
Linoleic acid metabolism	hsa00591	7.91
Serotonergic synapse	hsa04726	5.84
Metabolic pathways	hsa01100	2.49

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Xenobiotics	R-HSA-211981	8.66
Biological oxidations	R-HSA-211859	5.55
CYP2E1 reactions	R-HSA-211999	9.52
Arachidonic acid metabolism	R-HSA-2142753	7.34
Cytochrome P450 - arranged by substrate type	R-HSA-211897	7.08
Phase 1 - Functionalization of compounds	R-HSA-211945	6.7
Metabolism	R-HSA-1430728	2.34
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	R-HSA-2142670	9.98
Metabolism of lipids and lipoproteins	R-HSA-556833	3.79
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	R-HSA-2142816	9.81

Associated GO terms for Molecular function

GO term	GO ID	GO IC
monooxygenase activity	GO:0004497	5.1
limonene monooxygenase activity	GO:0019113	9.05
drug binding	GO:0008144	5.03
binding	GO:0005488	0.18
heterocyclic compound binding	GO:1901363	1.06
oxidoreductase activity	GO:0016491	3.12
cation binding	GO:0043169	1.4
oxidoreductase activity, acting on CH or CH2 groups	GO:0016725	7.44
transition metal ion binding	GO:0046914	2.48
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	GO:0016709	6.07
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	GO:0016705	4.65
ion binding	GO:0043167	1.36
iron ion binding	GO:0005506	4.65
metal ion binding	GO:0046872	1.41
(S)-limonene 6-monooxygenase activity	GO:0018675	9.05
(S)-limonene 7-monooxygenase activity	GO:0018676	9.05
heme binding	GO:0020037	4.86
catalytic activity	GO:0003824	1.05
caffeine oxidase activity	GO:0034875	8.35
cholesterol 25-hydroxylase activity	GO:0001567	9.05
oxygen binding	GO:0019825	5.89
tetrapyrrole binding	GO:0046906	4.8
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor	GO:0033695	8.35
organic cyclic compound binding	GO:0097159	1.05
(R)-limonene 6-monooxygenase activity	GO:0052741	9.05
steroid hydroxylase activity	GO:0008395	6.3
arachidonic acid epoxygenase activity	GO:0008392	7.03
arachidonic acid monooxygenase activity	GO:0008391	7.03