| Disease ID | Disease name | Source of annotation with DCTN1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 168605 | PERRY SYNDROME | OMIM, HUMSAVAR | link to OMIM | 1 | DCTN1 |
| PS105400 | AMYOTROPHIC LATERAL SCLEROSIS | OMIM, HUMSAVAR | link to OMIM | 27 | CHCHD10, FIG4, ERBB4, SQSTM1, ATXN2, UBQLN2, DCTN1, FUS, NEFH, PFN1, VAPB, MATR3, ALS2, TBK1, SPG11, TARDBP, TUBA4A, SIGMAR1, SOD1, CHMP2B, PRPH, ANG, VCP, OPTN, C9orf72, HNRNPA1, SETX |
| 607641 | NEURONOPATHY, DISTAL HEREDITARY MOTOR, TYPE VIIB | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | DCTN1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Vasopressin-regulated water reabsorption | hsa04962 | 7.18 |
| Huntington's disease | hsa05016 | 5.17 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Recruitment of mitotic centrosome proteins and complexes | R-HSA-380270 | 6.68 |
| Organelle biogenesis and maintenance | R-HSA-1852241 | 4.63 |
| Unfolded Protein Response (UPR) | R-HSA-381119 | 6.56 |
| Regulation of PLK1 Activity at G2/M Transition | R-HSA-2565942 | 6.66 |
| Loss of proteins required for interphase microtubule organization from the centrosome | R-HSA-380284 | 7.03 |
| Centrosome maturation | R-HSA-380287 | 6.68 |
| Loss of Nlp from mitotic centrosomes | R-HSA-380259 | 7.03 |
| Immune System | R-HSA-168256 | 2.37 |
| Mitotic G2-G2/M phases | R-HSA-453274 | 6.04 |
| Metabolism of proteins | R-HSA-392499 | 3.41 |
| XBP1(S) activates chaperone genes | R-HSA-381038 | 7.25 |
| Anchoring of the basal body to the plasma membrane | R-HSA-5620912 | 6.51 |
| Cell Cycle, Mitotic | R-HSA-69278 | 4.16 |
| MHC class II antigen presentation | R-HSA-2132295 | 6.01 |
| Cell Cycle | R-HSA-1640170 | 3.89 |
| IRE1alpha activates chaperones | R-HSA-381070 | 7.2 |
| Assembly of the primary cilium | R-HSA-5617833 | 5.44 |
| Adaptive Immune System | R-HSA-1280218 | 3.19 |
| G2/M Transition | R-HSA-69275 | 6.06 |
| GO term | GO ID | GO IC |
|---|---|---|
| hydrolase activity | GO:0016787 | 1.9 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | GO:0016818 | 3.03 |
| catalytic activity | GO:0003824 | 1.05 |
| dynein binding | GO:0045502 | 6.44 |
| nucleoside-triphosphatase activity | GO:0017111 | 3.09 |
| hydrolase activity, acting on acid anhydrides | GO:0016817 | 3.03 |
| pyrophosphatase activity | GO:0016462 | 3.04 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| motor activity | GO:0003774 | 4.81 |