| Disease ID | Disease name | Source of annotation with DDB2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 278740 | XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP E | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | DDB2 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Ubiquitin mediated proteolysis | hsa04120 | 5.63 |
| p53 signaling pathway | hsa04115 | 6.56 |
| Hepatitis B | hsa05161 | 5.52 |
| Nucleotide excision repair | hsa03420 | 7.15 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| DNA Repair | R-HSA-73894 | 5.8 |
| Global Genomic NER (GG-NER) | R-HSA-109970 | 7.89 |
| Dual incision reaction in GG-NER | R-HSA-73941 | 8.59 |
| Nucleotide Excision Repair | R-HSA-73885 | 7.34 |
| Formation of incision complex in GG-NER | R-HSA-73935 | 8.59 |
| GO term | GO ID | GO IC |
|---|---|---|
| ubiquitin-like protein transferase activity | GO:0019787 | 3.69 |
| nucleic acid binding | GO:0003676 | 1.44 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| damaged DNA binding | GO:0003684 | 5.58 |
| catalytic activity | GO:0003824 | 1.05 |
| transferase activity | GO:0016740 | 1.95 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| DNA binding | GO:0003677 | 1.92 |
| ubiquitin-protein transferase activity | GO:0004842 | 3.73 |
| heterocyclic compound binding | GO:1901363 | 1.06 |