Gene table of DDIT3 : DNA damage inducible transcript 3

Gene-disease associations table

Disease ID	Disease name	Source of annotation with DDIT3	OMIM link	Number of associated genes	genes
613488	MYXOID LIPOSARCOMA	OMIM	link to OMIM	1	DDIT3

Download the gene annotation in CSV format

Annotation of the gene DDIT3

Associated genes in ENSEMBL

ENSG00000175197

Associated proteins - SwissProt Accession ID

P35638

Associated PDB IDs

Cytogenetic Band

12q13.3

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Protein processing in endoplasmic reticulum	hsa04141	5.35
Transcriptional misregulation in cancer	hsa05202	5.21
Non-alcoholic fatty liver disease (NAFLD)	hsa04932	5.51
MAPK signaling pathway	hsa04010	4.63

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
PERK regulates gene expression	R-HSA-381042	8.18
Unfolded Protein Response (UPR)	R-HSA-381119	6.56
ATF6-alpha activates chaperones	R-HSA-381033	9.4
ATF4 activates genes	R-HSA-380994	8.34
ATF6-alpha activates chaperone genes	R-HSA-381183	9.66
Metabolism of proteins	R-HSA-392499	3.41

Associated GO terms for Molecular function

GO term	GO ID	GO IC
cAMP response element binding protein binding	GO:0008140	7.54
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
core promoter proximal region DNA binding	GO:0001159	3.82
leucine zipper domain binding	GO:0043522	7.34
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0001077	4.31
nucleic acid binding transcription factor activity	GO:0001071	2.65
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
heterocyclic compound binding	GO:1901363	1.06
sequence-specific DNA binding	GO:0043565	2.79
sequence-specific double-stranded DNA binding	GO:1990837	3.2
transcription corepressor activity	GO:0003714	4.33
transcription cofactor activity	GO:0003712	3.44
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
core promoter proximal region sequence-specific DNA binding	GO:0000987	3.83
double-stranded DNA binding	GO:0003690	3.09
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0000982	3.94
identical protein binding	GO:0042802	2.63
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
transcription factor binding	GO:0008134	3.46
regulatory region nucleic acid binding	GO:0001067	3.03
protein homodimerization activity	GO:0042803	3.16
protein domain specific binding	GO:0019904	3.32
LRR domain binding	GO:0030275	6.91
protein dimerization activity	GO:0046983	2.72
transcription regulatory region DNA binding	GO:0044212	3.03
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001228	3.98
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
RNA polymerase II core promoter proximal region sequence-specific DNA binding	GO:0000978	3.88
protein heterodimerization activity	GO:0046982	3.64
binding	GO:0005488	0.18