Gene table of DDX11 : DEAD/H-box helicase 11

Gene-disease associations table

Disease ID	Disease name	Source of annotation with DDX11	OMIM link	Number of associated genes	genes
613398	WARSAW BREAKAGE SYNDROME	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	DDX11

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Annotation of the gene DDX11

Associated genes in ENSEMBL

ENSG00000013573

Associated proteins - SwissProt Accession ID

Q96FC9

Associated PDB IDs

Cytogenetic Band

12p11.21

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
IRE1alpha activates chaperones	R-HSA-381070	7.2
Unfolded Protein Response (UPR)	R-HSA-381119	6.56
XBP1(S) activates chaperone genes	R-HSA-381038	7.25
Metabolism of proteins	R-HSA-392499	3.41

Associated GO terms for Molecular function

GO term	GO ID	GO IC
ATPase activity	GO:0016887	3.65
ATP-dependent helicase activity	GO:0008026	5.12
purine ribonucleoside triphosphate binding	GO:0035639	2.22
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
DNA helicase activity	GO:0003678	5.73
nucleotide binding	GO:0000166	1.96
heterocyclic compound binding	GO:1901363	1.06
purine nucleoside binding	GO:0001883	2.22
nucleoside binding	GO:0001882	2.21
cation binding	GO:0043169	1.4
metal cluster binding	GO:0051540	5.55
ATPase activity, coupled	GO:0042623	3.97
ion binding	GO:0043167	1.36
nucleoside phosphate binding	GO:1901265	1.96
ribonucleoside binding	GO:0032549	2.22
purine nucleotide binding	GO:0017076	2.19
double-stranded DNA binding	GO:0003690	3.09
metal ion binding	GO:0046872	1.41
single-stranded DNA binding	GO:0003697	5.17
ATP binding	GO:0005524	2.43
hydrolase activity	GO:0016787	1.9
ATP-dependent DNA helicase activity	GO:0004003	6.13
nucleoside-triphosphatase activity	GO:0017111	3.09
helicase activity	GO:0004386	4.69
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
DNA-dependent ATPase activity	GO:0008094	5.31
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO:0016818	3.03
4 iron, 4 sulfur cluster binding	GO:0051539	6.0
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
iron-sulfur cluster binding	GO:0051536	5.55
hydrolase activity, acting on acid anhydrides	GO:0016817	3.03
pyrophosphatase activity	GO:0016462	3.04
adenyl ribonucleotide binding	GO:0032559	2.41
RNA binding	GO:0003723	2.36
protein binding	GO:0005515	0.46
purine NTP-dependent helicase activity	GO:0070035	5.12
purine ribonucleotide binding	GO:0032555	2.2
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19