Gene table of DLAT : dihydrolipoamide S-acetyltransferase

Gene-disease associations table

Disease IDDisease nameSource of annotation with DLATOMIM linkNumber of associated genesgenes
PS312170PYRUVATE DEHYDROGENASE COMPLEX DEFICIENCYClinVar, OMIM link to OMIM 6PDHX, PDHA1, PDHB, PDP1, LIAS, DLAT

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Annotation of the gene DLAT

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Pyruvate metabolismhsa006207.45
Carbon metabolismhsa012006.03
Metabolic pathwayshsa011002.49
Glycolysis / Gluconeogenesishsa000106.64
Citrate cycle (TCA cycle)hsa000207.86
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Pyruvate metabolism and Citric Acid (TCA) cycleR-HSA-714067.56
Regulation of pyruvate dehydrogenase (PDH) complexR-HSA-2041749.18
The citric acid (TCA) cycle and respiratory electron transportR-HSA-14285175.71
Pyruvate metabolismR-HSA-702688.52
MetabolismR-HSA-14307282.34
Signal TransductionR-HSA-1625821.78
Signaling by Retinoic AcidR-HSA-53625177.62
Associated GO terms for Molecular function
GO termGO IDGO IC
pyruvate dehydrogenase activityGO:00047387.95
dihydrolipoamide S-acyltransferase activityGO:00305239.74
S-acyltransferase activityGO:00164176.37
pyruvate dehydrogenase (NAD+) activityGO:00346047.95
pyruvate dehydrogenase [NAD(P)+] activityGO:00346037.95
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptorGO:00166206.13
catalytic activityGO:00038241.05
transferase activityGO:00167401.95
oxidoreductase activity, acting on the aldehyde or oxo group of donorsGO:00169035.87
transferase activity, transferring acyl groupsGO:00167464.2
bindingGO:00054880.18
protein bindingGO:00055150.46
transferase activity, transferring acyl groups other than amino-acyl groupsGO:00167474.37
dihydrolipoyllysine-residue acetyltransferase activityGO:00047429.74
acetyltransferase activityGO:00164075.1
S-acetyltransferase activityGO:00164189.05
oxidoreductase activityGO:00164913.12