Disease ID | Disease name | Source of annotation with DLC1 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
114500 | COLORECTAL CANCER | OMIM | link to OMIM | 30 | TLR4, RAD54B, PTPRJ, TP53, EP300, PTPN12, ODC1, FLCN, TLR2, BAX, PLA2G2A, AURKA, NRAS, APC, MCC, TRIM28, MLH3, AKT1, MT-CO1, AXIN2, CTNNB1, PDGFRL, PIK3CA, KAT5, DCC, BRAF, CCND1, FGFR3, DLC1, BUB1B |
Download the gene annotation in CSV format
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Rho GTPase cycle | R-HSA-194840 | 6.04 |
Signaling by Rho GTPases | R-HSA-194315 | 4.43 |
Signal Transduction | R-HSA-162582 | 1.78 |
GO term | GO ID | GO IC |
---|---|---|
SH2 domain binding | GO:0042169 | 6.34 |
enzyme regulator activity | GO:0030234 | 2.85 |
GTPase activator activity | GO:0005096 | 4.11 |
lipid binding | GO:0008289 | 3.26 |
GTPase regulator activity | GO:0030695 | 4.01 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
enzyme activator activity | GO:0008047 | 3.56 |
molecular function regulator | GO:0098772 | 2.51 |
nucleoside-triphosphatase regulator activity | GO:0060589 | 3.92 |
protein domain specific binding | GO:0019904 | 3.32 |