Gene table of DLC1 : DLC1 Rho GTPase activating protein

Gene-disease associations table

Disease IDDisease nameSource of annotation with DLC1OMIM linkNumber of associated genesgenes
114500COLORECTAL CANCEROMIM link to OMIM 30TLR4, RAD54B, PTPRJ, TP53, EP300, PTPN12, ODC1, FLCN, TLR2, BAX, PLA2G2A, AURKA, NRAS, APC, MCC, TRIM28, MLH3, AKT1, MT-CO1, AXIN2, CTNNB1, PDGFRL, PIK3CA, KAT5, DCC, BRAF, CCND1, FGFR3, DLC1, BUB1B

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Annotation of the gene DLC1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Rho GTPase cycleR-HSA-1948406.04
Signaling by Rho GTPasesR-HSA-1943154.43
Signal TransductionR-HSA-1625821.78
Associated GO terms for Molecular function
GO termGO IDGO IC
SH2 domain bindingGO:00421696.34
enzyme regulator activityGO:00302342.85
GTPase activator activityGO:00050964.11
lipid bindingGO:00082893.26
GTPase regulator activityGO:00306954.01
bindingGO:00054880.18
protein bindingGO:00055150.46
enzyme activator activityGO:00080473.56
molecular function regulatorGO:00987722.51
nucleoside-triphosphatase regulator activityGO:00605893.92
protein domain specific bindingGO:00199043.32