Gene table of DNASE1 : deoxyribonuclease 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with DNASE1OMIM linkNumber of associated genesgenes
152700SYSTEMIC LUPUS ERYTHEMATOSUSOMIM link to OMIM 6FCGR2A, PTPN22, CTLA4, TREX1, FCGR2B, DNASE1

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Annotation of the gene DNASE1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
Associated REACTOME pathways
Associated GO terms for Molecular function
GO termGO IDGO IC
hydrolase activityGO:00167871.9
cytoskeletal protein bindingGO:00080923.02
nuclease activityGO:00045184.33
endonuclease activityGO:00045194.78
catalytic activityGO:00038241.05
endodeoxyribonuclease activityGO:00045205.81
hydrolase activity, acting on ester bondsGO:00167883.1
actin bindingGO:00037793.74
deoxyribonuclease activityGO:00045365.48
deoxyribonuclease I activityGO:00045309.05
bindingGO:00054880.18
protein bindingGO:00055150.46
endodeoxyribonuclease activity, producing 5'-phosphomonoestersGO:00168887.25
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoestersGO:00168935.83