Gene table of DNMT3B : DNA methyltransferase 3 beta

Gene-disease associations table

Disease ID	Disease name	Source of annotation with DNMT3B	OMIM link	Number of associated genes	genes
PS242860	IMMUNODEFICIENCY-CENTROMERIC INSTABILITY-FACIAL ANOMALIES	ClinVar, OMIM, HUMSAVAR	link to OMIM	4	HELLS, CDCA7, ZBTB24, DNMT3B

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Metabolic pathways	hsa01100	2.49
Cysteine and methionine metabolism	hsa00270	7.56
MicroRNAs in cancer	hsa05206	5.38

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Negative epigenetic regulation of rRNA expression	R-HSA-5250941	6.75
DNA methylation	R-HSA-5334118	8.03
NoRC negatively regulates rRNA expression	R-HSA-427413	6.81
Epigenetic regulation of gene expression	R-HSA-212165	6.46
PRC2 methylates histones and DNA	R-HSA-212300	7.7
Gene Expression	R-HSA-74160	2.72

Associated GO terms for Molecular function

GO term	GO ID	GO IC
heterocyclic compound binding	GO:1901363	1.06
enzyme binding	GO:0019899	2.27
unmethylated CpG binding	GO:0045322	7.95
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
methyltransferase activity	GO:0008168	4.35
DNA-methyltransferase activity	GO:0009008	8.13
sequence-specific DNA binding	GO:0043565	2.79
transcription corepressor activity	GO:0003714	4.33
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates	GO:0051718	8.64
transcription cofactor activity	GO:0003712	3.44
ion binding	GO:0043167	1.36
DNA (cytosine-5-)-methyltransferase activity	GO:0003886	8.35
transferase activity	GO:0016740	1.95
transferase activity, transferring one-carbon groups	GO:0016741	4.3
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
metal ion binding	GO:0046872	1.41
histone deacetylase binding	GO:0042826	5.08
cation binding	GO:0043169	1.4
S-adenosylmethionine-dependent methyltransferase activity	GO:0008757	4.81
catalytic activity	GO:0003824	1.05
organic cyclic compound binding	GO:0097159	1.05
protein binding	GO:0005515	0.46
chromatin binding	GO:0003682	3.64