Disease ID | Disease name | Source of annotation with DRD3 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS190300 | TREMOR, HEREDITARY ESSENTIAL | OMIM | link to OMIM | 3 | FUS, TENM4, DRD3 |
181500 | SCHIZOPHRENIA | OMIM | link to OMIM | 17 | COMT, DISC2, MTHFR, DISC1, CHI3L1, SYN2, MC4R, DAO, AKT1, HTR2A, APOL2, DTNBP1, SETD1A, DRD3, APOL4, RTN4R, DAOA |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Dopaminergic synapse | hsa04728 | 5.69 |
Neuroactive ligand-receptor interaction | hsa04080 | 4.58 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Amine ligand-binding receptors | R-HSA-375280 | 7.59 |
Signaling by GPCR | R-HSA-372790 | 2.68 |
G alpha (i) signalling events | R-HSA-418594 | 5.1 |
Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
Signal Transduction | R-HSA-162582 | 1.78 |
GPCR downstream signaling | R-HSA-388396 | 3.07 |
GPCR ligand binding | R-HSA-500792 | 4.19 |
Dopamine receptors | R-HSA-390651 | 10.66 |
GO term | GO ID | GO IC |
---|---|---|
signaling receptor activity | GO:0038023 | 2.49 |
drug binding | GO:0008144 | 5.03 |
molecular transducer activity | GO:0060089 | 2.32 |
dopamine neurotransmitter receptor activity | GO:0004952 | 7.79 |
dopamine binding | GO:0035240 | 7.34 |
binding | GO:0005488 | 0.18 |
signal transducer activity | GO:0004871 | 2.28 |
G-protein coupled receptor binding | GO:0001664 | 4.18 |
dopamine neurotransmitter receptor activity, coupled via Gs | GO:0001588 | 7.95 |
G-protein coupled receptor activity | GO:0004930 | 2.95 |
neurotransmitter receptor activity | GO:0030594 | 5.5 |
D1 dopamine receptor binding | GO:0031748 | 7.66 |
protein domain specific binding | GO:0019904 | 3.32 |
organic cyclic compound binding | GO:0097159 | 1.05 |
dopamine neurotransmitter receptor activity, coupled via Gi/Go | GO:0001591 | 8.64 |
transmembrane signaling receptor activity | GO:0004888 | 2.57 |
protein binding | GO:0005515 | 0.46 |
catecholamine binding | GO:1901338 | 6.97 |
dopamine receptor binding | GO:0050780 | 6.85 |
receptor binding | GO:0005102 | 2.43 |
transmembrane receptor activity | GO:0099600 | 2.53 |
receptor activity | GO:0004872 | 2.32 |