Gene table of EIF2AK3 : eukaryotic translation initiation factor 2 alpha kinase 3

Gene-disease associations table

Disease ID	Disease name	Source of annotation with EIF2AK3	OMIM link	Number of associated genes	genes
226980	EPIPHYSEAL DYSPLASIA, MULTIPLE, WITH EARLY-ONSET DIABETES MELLITUS	OMIM, HUMSAVAR	link to OMIM	1	EIF2AK3

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Alzheimer's disease	hsa05010	5.34
Protein processing in endoplasmic reticulum	hsa04141	5.35
Herpes simplex infection	hsa05168	5.08
Non-alcoholic fatty liver disease (NAFLD)	hsa04932	5.51
Influenza A	hsa05164	5.21
Hepatitis C	hsa05160	5.68
Measles	hsa05162	5.6
Epstein-Barr virus infection	hsa05169	4.97

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
PERK regulates gene expression	R-HSA-381042	8.18
Unfolded Protein Response (UPR)	R-HSA-381119	6.56
Metabolism of proteins	R-HSA-392499	3.41

Associated GO terms for Molecular function

GO term	GO ID	GO IC
purine ribonucleoside triphosphate binding	GO:0035639	2.22
heat shock protein binding	GO:0031072	5.24
enzyme binding	GO:0019899	2.27
binding	GO:0005488	0.18
heterocyclic compound binding	GO:1901363	1.06
purine nucleoside binding	GO:0001883	2.22
nucleoside binding	GO:0001882	2.21
nucleotide binding	GO:0000166	1.96
protein serine/threonine kinase activity	GO:0004674	3.64
transferase activity	GO:0016740	1.95
nucleoside phosphate binding	GO:1901265	1.96
ribonucleoside binding	GO:0032549	2.22
purine nucleotide binding	GO:0017076	2.19
protein kinase activity	GO:0004672	3.27
eukaryotic translation initiation factor 2alpha kinase activity	GO:0004694	8.35
Hsp90 protein binding	GO:0051879	6.37
identical protein binding	GO:0042802	2.63
protein homodimerization activity	GO:0042803	3.16
kinase activity	GO:0016301	2.93
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
protein phosphatase binding	GO:0019903	4.93
phosphatase binding	GO:0019902	4.63
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
adenyl ribonucleotide binding	GO:0032559	2.41
ATP binding	GO:0005524	2.43
protein binding	GO:0005515	0.46
organic cyclic compound binding	GO:0097159	1.05
purine ribonucleotide binding	GO:0032555	2.2
protein dimerization activity	GO:0046983	2.72
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19