| Disease ID | Disease name | Source of annotation with EIF2B3 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 603896 | LEUKOENCEPHALOPATHY WITH VANISHING WHITE MATTER | ClinVar, OMIM, HUMSAVAR | link to OMIM | 5 | EIF2B3, EIF2B2, EIF2B1, EIF2B5, EIF2B4 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| RNA transport | hsa03013 | 5.37 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Gene Expression | R-HSA-74160 | 2.72 |
| Metabolism of proteins | R-HSA-392499 | 3.41 |
| Translation | R-HSA-72766 | 5.8 |
| Recycling of eIF2:GDP | R-HSA-72731 | 9.98 |
| Cap-dependent Translation Initiation | R-HSA-72737 | 6.18 |
| Eukaryotic Translation Initiation | R-HSA-72613 | 6.18 |
| GO term | GO ID | GO IC |
|---|---|---|
| nucleotidyltransferase activity | GO:0016779 | 4.81 |
| nucleic acid binding | GO:0003676 | 1.44 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| translation factor activity, RNA binding | GO:0008135 | 5.07 |
| guanyl-nucleotide exchange factor activity | GO:0005085 | 4.02 |
| catalytic activity | GO:0003824 | 1.05 |
| transferase activity | GO:0016740 | 1.95 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| transferase activity, transferring phosphorus-containing groups | GO:0016772 | 2.77 |
| RNA binding | GO:0003723 | 2.36 |
| molecular function regulator | GO:0098772 | 2.51 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| translation initiation factor activity | GO:0003743 | 5.7 |