Gene table of EPHA2 : EPH receptor A2

Gene-disease associations table

Disease ID	Disease name	Source of annotation with EPHA2	OMIM link	Number of associated genes	genes
PS116200	CATARACT	ClinVar, OMIM, HUMSAVAR	link to OMIM	33	GCNT2, CRYGD, VIM, CRYBB2, PITX3, UNC45B, BFSP1, GJA8, MAF, AGK, EPHA2, CRYBB3, MIP, CRYBA2, CRYGS, CRYBB1, FYCO1, SIPA1L3, CRYAB, GJA3, BFSP2, TDRD7, HSF4, CHMP4B, CRYAA, LIM2, WFS1, CRYBA4, LSS, CRYBA1, CRYGB, CRYGC, NHS

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
EPH-ephrin mediated repulsion of cells	R-HSA-3928665	7.34
Axon guidance	R-HSA-422475	3.93
EPH-Ephrin signaling	R-HSA-2682334	6.43
EPHA-mediated growth cone collapse	R-HSA-3928663	7.89
Developmental Biology	R-HSA-1266738	3.48

Associated GO terms for Molecular function

GO term	GO ID	GO IC
signaling receptor activity	GO:0038023	2.49
purine ribonucleoside triphosphate binding	GO:0035639	2.22
molecular transducer activity	GO:0060089	2.32
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
heterocyclic compound binding	GO:1901363	1.06
purine nucleoside binding	GO:0001883	2.22
nucleoside binding	GO:0001882	2.21
transmembrane signaling receptor activity	GO:0004888	2.57
nucleotide binding	GO:0000166	1.96
transmembrane receptor protein tyrosine kinase activity	GO:0004714	5.55
protein tyrosine kinase activity	GO:0004713	4.54
ribonucleoside binding	GO:0032549	2.22
purine nucleotide binding	GO:0017076	2.19
protein kinase activity	GO:0004672	3.27
ATP binding	GO:0005524	2.43
kinase activity	GO:0016301	2.93
nucleoside phosphate binding	GO:1901265	1.96
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
ephrin receptor activity	GO:0005003	6.79
transferase activity	GO:0016740	1.95
adenyl ribonucleotide binding	GO:0032559	2.41
ribonucleotide binding	GO:0032553	2.19
protein binding	GO:0005515	0.46
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
purine ribonucleotide binding	GO:0032555	2.2
transmembrane receptor protein kinase activity	GO:0019199	5.32
purine ribonucleoside binding	GO:0032550	2.22
transmembrane receptor activity	GO:0099600	2.53
receptor activity	GO:0004872	2.32