Gene table of EZH2 : enhancer of zeste 2 polycomb repressive complex 2 subunit

Gene-disease associations table

Disease IDDisease nameSource of annotation with EZH2OMIM linkNumber of associated genesgenes
277590WEAVER SYNDROMEClinVar, OMIM, HUMSAVAR link to OMIM 1EZH2

Download the gene annotation in CSV format

Annotation of the gene EZH2

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
MicroRNAs in cancerhsa052065.38
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Oxidative Stress Induced SenescenceR-HSA-25595806.51
Cellular SenescenceR-HSA-25595835.7
Epigenetic regulation of gene expressionR-HSA-2121656.46
PRC2 methylates histones and DNAR-HSA-2123007.7
Cellular responses to stressR-HSA-22627524.56
Chromatin organizationR-HSA-48397265.19
PKMTs methylate histone lysinesR-HSA-32148417.66
Gene ExpressionR-HSA-741602.72
Chromatin modifying enzymesR-HSA-32475095.19
Associated GO terms for Molecular function
GO termGO IDGO IC
histone-lysine N-methyltransferase activityGO:00180245.93
histone methyltransferase activityGO:00420545.68
nucleic acid bindingGO:00036761.44
lysine N-methyltransferase activityGO:00162785.7
protein-lysine N-methyltransferase activityGO:00162795.71
chromatin DNA bindingGO:00314905.37
protein methyltransferase activityGO:00082765.33
macromolecular complex bindingGO:00448772.61
bindingGO:00054880.18
histone methyltransferase activity (H3-K27 specific)GO:00469768.64
DNA bindingGO:00036771.92
methyltransferase activityGO:00081684.35
heterocyclic compound bindingGO:19013631.06
sequence-specific DNA bindingGO:00435652.79
structure-specific DNA bindingGO:00435664.98
transferase activityGO:00167401.95
transferase activity, transferring one-carbon groupsGO:00167414.3
ribonucleoprotein complex bindingGO:00430215.15
S-adenosylmethionine-dependent methyltransferase activityGO:00087574.81
regulatory region nucleic acid bindingGO:00010673.03
catalytic activityGO:00038241.05
N-methyltransferase activityGO:00081705.26
core promoter bindingGO:00010474.71
promoter-specific chromatin bindingGO:19908417.34
transcription regulatory region DNA bindingGO:00442123.03
organic cyclic compound bindingGO:00971591.05
RNA bindingGO:00037232.36
protein bindingGO:00055150.46
regulatory region DNA bindingGO:00009753.03
chromatin bindingGO:00036823.64