Gene table of FH : fumarate hydratase

Gene-disease associations table

Disease IDDisease nameSource of annotation with FHOMIM linkNumber of associated genesgenes
150800HEREDITARY LEIOMYOMATOSIS AND RENAL CELL CANCERClinVar, OMIM, HUMSAVAR link to OMIM 1FH
606812FUMARASE DEFICIENCYClinVar, OMIM, HUMSAVAR link to OMIM 1FH

Download the gene annotation in CSV format

Annotation of the gene FH

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Pyruvate metabolismhsa006207.45
Metabolic pathwayshsa011002.49
Renal cell carcinomahsa052116.6
Pathways in cancerhsa052003.98
Carbon metabolismhsa012006.03
Citrate cycle (TCA cycle)hsa000207.86
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
The citric acid (TCA) cycle and respiratory electron transportR-HSA-14285175.71
Pyruvate metabolism and Citric Acid (TCA) cycleR-HSA-714067.56
MetabolismR-HSA-14307282.34
Citric acid cycle (TCA cycle)R-HSA-714038.73
Associated GO terms for Molecular function
GO termGO IDGO IC
carbon-oxygen lyase activityGO:00168355.46
hydro-lyase activityGO:00168365.81
catalytic activityGO:00038241.05
bindingGO:00054880.18
protein bindingGO:00055150.46
fumarate hydratase activityGO:00043339.74
lyase activityGO:00168294.53