Gene table of FOXC1 : forkhead box C1

Gene-disease associations table

Disease IDDisease nameSource of annotation with FOXC1OMIM linkNumber of associated genesgenes
601631IRIDOGONIODYSGENESIS, TYPE 1ClinVar, OMIM, HUMSAVAR link to OMIM 1FOXC1
308500IRIS HYPOPLASIA WITH GLAUCOMAClinVar link to OMIM 1FOXC1
602482AXENFELD-RIEGER SYNDROME, TYPE 3ClinVar, OMIM, HUMSAVAR link to OMIM 1FOXC1
604229PETERS ANOMALYHUMSAVAR link to OMIM 4FOXC1, PITX2, CYP1B1, PAX6

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Annotation of the gene FOXC1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways
Associated REACTOME pathways
Associated GO terms for Molecular function
GO termGO IDGO IC
RNA polymerase II regulatory region DNA bindingGO:00010123.36
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingGO:00012283.98
nucleic acid binding transcription factor activityGO:00010712.65
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
heterocyclic compound bindingGO:19013631.06
sequence-specific DNA bindingGO:00435652.79
sequence-specific double-stranded DNA bindingGO:19908373.2
double-stranded DNA bindingGO:00036903.09
RNA polymerase II transcription factor activity, sequence-specific DNA bindingGO:00009813.29
transcription factor bindingGO:00081343.46
regulatory region nucleic acid bindingGO:00010673.03
DNA binding, bendingGO:00083016.74
transcription regulatory region DNA bindingGO:00442123.03
transcription factor activity, sequence-specific DNA bindingGO:00037002.65
organic cyclic compound bindingGO:00971591.05
transcription factor activity, RNA polymerase II distal enhancer sequence-specific bindingGO:00037055.23
transcription regulatory region sequence-specific DNA bindingGO:00009763.24
RNA polymerase II regulatory region sequence-specific DNA bindingGO:00009773.37
protein bindingGO:00055150.46
regulatory region DNA bindingGO:00009753.03
bindingGO:00054880.18