Gene table of FUS : FUS RNA binding protein

Gene-disease associations table

Disease IDDisease nameSource of annotation with FUSOMIM linkNumber of associated genesgenes
PS190300TREMOR, HEREDITARY ESSENTIALClinVar, OMIM, HUMSAVAR link to OMIM 3FUS, TENM4, DRD3
PS105400AMYOTROPHIC LATERAL SCLEROSISClinVar, OMIM, HUMSAVAR link to OMIM 27CHCHD10, FIG4, ERBB4, SQSTM1, ATXN2, UBQLN2, DCTN1, FUS, NEFH, PFN1, VAPB, MATR3, ALS2, TBK1, SPG11, TARDBP, TUBA4A, SIGMAR1, SOD1, CHMP2B, PRPH, ANG, VCP, OPTN, C9orf72, HNRNPA1, SETX

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Annotation of the gene FUS

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Transcriptional misregulation in cancerhsa052025.21
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Gene ExpressionR-HSA-741602.72
mRNA Splicing - Major PathwayR-HSA-721636.15
Processing of Capped Intron-Containing Pre-mRNAR-HSA-722036.1
mRNA SplicingR-HSA-721726.15
Associated GO terms for Molecular function
GO termGO IDGO IC
myosin bindingGO:00170225.66
zinc ion bindingGO:00082702.66
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
nucleotide bindingGO:00001661.96
heterocyclic compound bindingGO:19013631.06
nucleoside phosphate bindingGO:19012651.96
cation bindingGO:00431691.4
transition metal ion bindingGO:00469142.48
transcription coactivator activityGO:00037134.04
transcription cofactor activityGO:00037123.44
ion bindingGO:00431671.36
transcription factor activity, transcription factor bindingGO:00009893.36
transcription factor activity, protein bindingGO:00009883.35
metal ion bindingGO:00468721.41
transcription factor bindingGO:00081343.46
identical protein bindingGO:00428022.63
steroid hormone receptor bindingGO:00352585.32
estrogen receptor bindingGO:00303316.05
poly(A) RNA bindingGO:00448222.69
nuclear hormone receptor bindingGO:00352574.7
ionotropic glutamate receptor bindingGO:00352556.56
glutamate receptor bindingGO:00352546.13
small molecule bindingGO:00360941.89
thyroid hormone receptor bindingGO:00469666.34
retinoid X receptor bindingGO:00469656.79
hormone receptor bindingGO:00514274.57
myosin V bindingGO:00314896.91
cytoskeletal protein bindingGO:00080923.02
organic cyclic compound bindingGO:00971591.05
RNA bindingGO:00037232.36
protein bindingGO:00055150.46
retinoic acid receptor bindingGO:00429745.83
receptor bindingGO:00051022.43
bindingGO:00054880.18