| Disease ID | Disease name | Source of annotation with GDI1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS309530 | MENTAL RETARDATION, NONSYNDROMIC, X-LINKED | ClinVar, OMIM, HUMSAVAR | link to OMIM | 25 | THOC2, HCFC1, RPS6KA3, USP9X, MID2, RAB39B, KIAA2022, ZNF81, PAK3, IQSEC2, DLG3, TSPAN7, ZDHHC15, ZNF711, KIF4A, ACSL4, BRWD3, IL1RAPL1, GDI1, SYP, ARHGEF6, ARX, DDX3X, GRIA3, FTSJ1 |
Download the gene annotation in CSV format
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Rho GTPase cycle | R-HSA-194840 | 6.04 |
| Signaling by Rho GTPases | R-HSA-194315 | 4.43 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| molecular function regulator | GO:0098772 | 2.51 |
| GTPase regulator activity | GO:0030695 | 4.01 |
| GDP-dissociation inhibitor activity | GO:0005092 | 7.17 |
| Rab GDP-dissociation inhibitor activity | GO:0005093 | 9.05 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| GTPase activator activity | GO:0005096 | 4.11 |
| Rab GTPase binding | GO:0017137 | 4.96 |
| enzyme binding | GO:0019899 | 2.27 |
| Ras GTPase binding | GO:0017016 | 4.2 |
| small GTPase binding | GO:0031267 | 4.13 |
| GTPase binding | GO:0051020 | 4.05 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| oxidoreductase activity | GO:0016491 | 3.12 |
| nucleoside-triphosphatase regulator activity | GO:0060589 | 3.92 |
| catalytic activity | GO:0003824 | 1.05 |
| enzyme activator activity | GO:0008047 | 3.56 |