Gene table of GDNF : glial cell derived neurotrophic factor

Gene-disease associations table

Disease IDDisease nameSource of annotation with GDNFOMIM linkNumber of associated genesgenes
PS142623HIRSCHSPRUNG DISEASEClinVar, OMIM, HUMSAVAR link to OMIM 21TSC2, KDR, GDNF, PTCH1, GFRA1, NTF3, IRAK3, EDN3, ZHX2, THBS4, AHNAK, POLR2F, FBN1, RET, CNTN5, DPYD, EDNRB, CREBBP, SEMA3D, FAT3, PLAU
171300PHEOCHROMOCYTOMAOMIM link to OMIM 8VHL, GDNF, SDHB, KIF1B, RET, MAX, TMEM127, SDHD
209880CENTRAL HYPOVENTILATION SYNDROME, CONGENITALClinVar, OMIM link to OMIM 6ASCL1, GDNF, EDN3, BDNF, PHOX2B, RET

Download the gene annotation in CSV format

Annotation of the gene GDNF

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
NCAM signaling for neurite out-growthR-HSA-3751654.9
Axon guidanceR-HSA-4224753.93
NCAM1 interactionsR-HSA-4190377.59
Developmental BiologyR-HSA-12667383.48
Associated GO terms for Molecular function
GO termGO IDGO IC
Ras guanyl-nucleotide exchange factor activityGO:00050884.31
growth factor activityGO:00080834.66
guanyl-nucleotide exchange factor activityGO:00050854.02
bindingGO:00054880.18
protein bindingGO:00055150.46
receptor bindingGO:00051022.43
molecular function regulatorGO:00987722.51
protein dimerization activityGO:00469832.72
identical protein bindingGO:00428022.63
protein homodimerization activityGO:00428033.16