| Disease ID | Disease name | Source of annotation with GNAL | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS128100 | DYSTONIA | ClinVar, OMIM, HUMSAVAR | link to OMIM | 18 | DRD2, GNAL, ANO3, SLC2A1, KCTD17, HPCA, THAP1, GCH1, PRRT2, ATP1A3, PNKD, PRKRA, COL6A3, TOR1A, CACNA1B, SGCE, TAF1, TUBB4A |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Calcium signaling pathway | hsa04020 | 5.22 |
| Chagas disease (American trypanosomiasis) | hsa05142 | 5.99 |
| Amoebiasis | hsa05146 | 5.82 |
| Olfactory transduction | hsa04740 | 4.13 |
| Dopaminergic synapse | hsa04728 | 5.69 |
| Parkinson's disease | hsa05012 | 5.59 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Adenylate cyclase inhibitory pathway | R-HSA-170670 | 9.18 |
| Adenylate cyclase activating pathway | R-HSA-170660 | 9.66 |
| G-protein mediated events | R-HSA-112040 | 7.49 |
| GPCR downstream signaling | R-HSA-388396 | 3.07 |
| Opioid Signalling | R-HSA-111885 | 6.64 |
| GABA receptor activation | R-HSA-977443 | 7.2 |
| Activation of GABAB receptors | R-HSA-991365 | 7.7 |
| Inhibition of adenylate cyclase pathway | R-HSA-997269 | 9.18 |
| GABA B receptor activation | R-HSA-977444 | 7.7 |
| Neuronal System | R-HSA-112316 | 4.82 |
| Signaling by GPCR | R-HSA-372790 | 2.68 |
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | R-HSA-112314 | 5.85 |
| Transmission across Chemical Synapses | R-HSA-112315 | 5.28 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| Olfactory Signaling Pathway | R-HSA-381753 | 4.27 |
| GO term | GO ID | GO IC |
|---|---|---|
| purine ribonucleoside triphosphate binding | GO:0035639 | 2.22 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| signal transducer activity | GO:0004871 | 2.28 |
| ion binding | GO:0043167 | 1.36 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| purine nucleoside binding | GO:0001883 | 2.22 |
| nucleoside binding | GO:0001882 | 2.21 |
| cation binding | GO:0043169 | 1.4 |
| pyrophosphatase activity | GO:0016462 | 3.04 |
| nucleotide binding | GO:0000166 | 1.96 |
| guanyl ribonucleotide binding | GO:0032561 | 3.73 |
| nucleoside phosphate binding | GO:1901265 | 1.96 |
| ribonucleoside binding | GO:0032549 | 2.22 |
| protein complex binding | GO:0032403 | 3.09 |
| purine nucleotide binding | GO:0017076 | 2.19 |
| metal ion binding | GO:0046872 | 1.41 |
| GTP binding | GO:0005525 | 3.78 |
| hydrolase activity | GO:0016787 | 1.9 |
| G-protein beta/gamma-subunit complex binding | GO:0031683 | 6.65 |
| GTPase activity | GO:0003924 | 4.31 |
| nucleoside-triphosphatase activity | GO:0017111 | 3.09 |
| small molecule binding | GO:0036094 | 1.89 |
| catalytic activity | GO:0003824 | 1.05 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | GO:0016818 | 3.03 |
| carbohydrate derivative binding | GO:0097367 | 2.03 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| hydrolase activity, acting on acid anhydrides | GO:0016817 | 3.03 |
| guanyl nucleotide binding | GO:0019001 | 3.73 |
| protein binding | GO:0005515 | 0.46 |
| purine ribonucleotide binding | GO:0032555 | 2.2 |
| purine ribonucleoside binding | GO:0032550 | 2.22 |
| ribonucleotide binding | GO:0032553 | 2.19 |